It’s Wednesday, and that means it’s time to break out the fantasy football flex rankings for Week 16 of the 2022 NFL season. If you’re new to the concept of flex rankings, these are simply the combined overall rankings for running back, wide receiver and tight end for each week during the fantasy football season. These are not suggestions for who to start in your flex spots.
This list is our initial rankings, but it will change a lot throughout the week. If you want all the latest updates, then be sure to check our staff rankings page. Promo code “RATPACK” gets you 20% off of any FTN subscription.
Week 16 Flex Rankings (2022) – Top 100
1. Derrick Henry vs. HOU (RB1)
2. Christian McCaffrey vs. WAS (RB2)
3. Justin Jefferson vs. NYG (WR1)
4. Austin Ekeler @ IND (RB3)
5. Tyreek Hill vs. GB (WR2)
6. Saquon Barkley @ MIN (RB4)
7. Dalvin Cook vs. NYG (RB5)
8. Josh Jacobs @ PIT (RB6)
9. Davante Adams @ PIT (WR3)
10. Travis Kelce vs. SEA (TE1)
11. Rhamondre Stevenson vs. CIN (RB7)
12. Ja’Marr Chase @ NE (WR4)
13. Aaron Jones @ MIA (RB8)
14. James Conner vs. TB (RB9)
15. Stefon Diggs @ CHI (WR5)
16. Nick Chubb vs. NO (RB10)
17. CeeDee Lamb vs. PHI (WR6)
18. Amon-Ra St. Brown @ CAR (WR7)
19. DK Metcalf @ KC (WR8)
20. Tony Pollard vs. PHI (RB11)
21. Alvin Kamara @ CLE (RB12)
22. Jaylen Waddle vs. GB (WR9)
23. Najee Harris vs. LV (RB13)
24. A.J. Brown @ DAL (WR10)
25. Kenneth Walker @ KC (RB14)
26. Travis Etienne @ NYJ (RB15)
27. Joe Mixon @ NE (RB16)
28. Chris Godwin @ ARI (WR11)
29. Jerick McKinnon vs. SEA (RB17)
30. Keenan Allen @ IND (WR12)
31. Miles Sanders @ DAL (RB18)
32. DeAndre Hopkins vs. TB (WR13)
33. Latavius Murray @ LA (RB19)
34. Ezekiel Elliott vs. PHI (RB20)
35. J.K. Dobbins vs. ATL (RB21)
36. Isiah Pacheco vs. SEA (RB22)
37. Raheem Mostert vs. GB (RB23)
38. Mike Williams @ IND (WR14)
39. Christian Watson @ MIA (WR15)
40. Tee Higgins @ NE (WR16)
41. DJ Moore vs. DET (WR17)
42. Mike Evans @ ARI (WR18)
43. David Montgomery vs. BUF (RB24)
44. Garrett Wilson vs. JAX (WR19)
45. Jerry Jeudy @ LA (WR20)
46. Christian Kirk @ NYJ (WR21)
47. Leonard Fournette @ ARI (RB25)
48. Michael Pittman Jr. vs. LAC (WR22)
49. JuJu Smith-Schuster vs. SEA (WR23)
50. Terry McLaurin @ SF (WR24)
51. D’Andre Swift @ CAR (RB26)
52. Devin Singletary @ CHI (RB27)
53. Cam Akers vs. DEN (RB28)
54. Zay Jones @ NYJ (WR25)
55. Zonovan Knight vs. JAX (RB29)
56. Jamaal Williams @ CAR (RB30)
57. Rachaad White @ ARI (RB31)
58. DeVonta Smith @ DAL (WR26)
59. Diontae Johnson vs. LV (WR27)
60. D’Onta Foreman vs. DET (RB32)
61. Mark Andrews vs. ATL (TE2)
62. Brandon Aiyuk vs. WAS (WR28)
63. Zack Moss vs. LAC (RB33)
64. Brian Robinson @ SF (RB34)
65. Marquise Brown vs. TB (WR29)
66. T.J. Hockenson vs. NYG (TE3)
67. Adam Thielen vs. NYG (WR30)
68. Cordarrelle Patterson @ BAL (RB35)
69. Tyler Allgeier @ BAL (RB36)
70. Darius Slayton @ MIN (WR31)
71. Gabe Davis @ CHI (WR32)
72. Chuba Hubbard vs. DET (RB37)
73. Allen Lazard @ MIA (WR33)
74. George Kittle vs. WAS (TE4)
75. Amari Cooper vs. NO (WR34)
76. Chris Olave @ CLE (WR35)
77. Drake London @ BAL (WR36)
78. Dalton Schultz vs. PHI (TE5)
79. George Pickens vs. LV (WR37)
80. Deon Jackson vs. LAC (RB38)
81. Antonio Gibson @ SF (RB39)
82. James Cook @ CHI (RB40)
83. Jakobi Meyers vs. CIN (WR38)
84. Marquise Goodwin @ KC (WR39)
85. Evan Engram @ NYJ (TE6)
86. DJ Chark @ CAR (WR40)
87. K.J. Osborn vs. NYG (WR41)
88. Joshua Palmer @ IND (WR42)
89. Michael Carter vs. JAX (RB41)
90. Mack Hollins @ PIT (WR43)
91. Pat Freiermuth vs. LV (TE7)
92. Curtis Samuel @ SF (WR44)
93. Greg Dulcich @ LA (TE8)
94. Taysom Hill @ CLE (TE9)
95. Tyler Boyd @ NE (WR45)
96. Tutu Atwell vs. DEN (WR46)
97. Donovan Peoples-Jones vs. NO (WR47)
98. Michael Gallup vs. PHI (WR48)
99. Parris Campbell vs. LAC (WR49)
100. Dawson Knox @ CHI (TE10)