Los Angeles Dodgers first baseman Freddie Freeman (ankle) is expected to return on Friday when the Dodgers host the Chicago Cubs. Freeman has been on the 10-day injured list after suffering a setback on the ankle he underwent surgery on. However, it appears the 35-year-old is only expected to miss a short period of time. Through his first four games of the regular season, Freeman has posted a modest .250/.250/.833 line with a double and two home runs. However, under the hood, Freeman has generated an elite .577 xwOBA, which suggests he should see significant positive regression in his batting average. While Freeman has been sidelined, Kike Hernandez has seen most of the time at first base. When Freeman returns, he should be viewed as a must-start high-end No. 1 first baseman.

Athletics first baseman Tyler Soderstrom (calf) is in the starting nine on Wednesday afternoon when they conclude their series against the San Diego Padres. Soderstrom was removed from Tuesday's contest due to a calf contusion. However, the injury was not serious, and the former first-round pick is already returning to action. He will cover first base and bat in the three-hole. Soderstrom has enjoyed an impressive start to the campaign as he has posted a .378/.440/.822 slash line with six long balls across 12 contests. He has generated a stellar .415 xwOBA with a .626 xSLG. He is a solid play in DFS facing San Diego right-hander Randy Vasquez.

Seattle Mariners second baseman Ryan Bliss (biceps) was placed on the 10-day injured list due to a left biceps tear. The 25-year-old reportedly suffered this injury during Tuesday's contest against the Houston Astros. In a corresponding move, the Mariners promoted Leo Rivas from Triple-A Tacoma. Bliss has had a starting role in the Seattle starting nine through the opening two weeks of the season. Through 11 games, Bliss has posted a .200/.282/.314 slash line with one double and one home run. Fantasy managers should expect Dylan Moore to see most of the time at the keystone, once veteran Jorge Polanco is cleared to return to the hot corner. Miles Mastrobuoni and Leo Rivas could also see occasional starts at second base as well.

San Diego Padres infielder Jake Cronenworth (ribs) is not in Wednesday's lineup when the Padres conclude a series with the Athletics. Cronenworth exited Tuesday's contest after feeling a pain in his ribs. Fantasy managers should monitor his status leading up to their next game against the Colorado Rockies on Friday evening. In addition, Cronenworth was hit by a pitch on Sunday in this same area, which is related to this injury. Instead, the Padres will give veteran infielder Jose Iglesias the starting nod at the keystone. Iglesias will bat in the six-hole. Through 12 games this season, Cronenworth has held a solid .257/.409/.486 slash line with two doubles and two round-trippers. If Cronenworth were to miss an extended period of time, Iglesias would likely have a clear role in the starting nine.

The Chicago White Sox placed outfielder Andrew Benintendi (groin) on the 10-day injured list (retroactive to April 7) on Wednesday and recalled outfielder Greg Jones from Triple-A Charlotte in a corresponding move. The White Sox also agreed to a minor-league deal with Travis Jankowski for additional outfield depth. The White Sox initially didn't believe Benintendi's left-groin strain was very serious, but the 30-year-old wasn't feeling as good as they thought he would, leading them to send him for more tests on Tuesday. It's a tough break for Benintendi, who had gotten off to a good start with a .290 average (9-for-31) with two home runs, six RBI and five runs scored in nine games played. Michael Taylor is starting in left field for the White Sox in Wednesday's game against the Cleveland Guardians, but Brooks Baldwin should also see playing time there with Benintendi on the shelf.