Indianapolis Colts vs. Tennessee Titans – Week 7 Betting Preview

The Week 7 matchup between the Indianapolis Colts and Tennessee Titans is probably the most important divisional game of the 2022 NFL season, thus far. The rivals are tied atop the AFC South, and Tennessee defeated Indianapolis just a few weeks ago.

A Titans victory might very well mean that the team is headed for its third straight AFC South title. Tennessee went into its Week 6 bye on a three-game winning streak. Indianapolis has managed to climb back above .500 with Jonathan Taylor missing the last two games because of a sprained ankle. 

Let’s take a look at some key statistics and information about this matchup.

When is Indianapolis Colts vs. Tennessee Titans Week 7? 

Date/Time: Oct. 23, 1 p.m. ET 
Arena: Nissan Stadium
How to watch: CBS
Opening odds: Titans -2 | IND+125, TEN -145 | O/U 42.5

Week 7 Colts vs. Titans Betting Odds 

Here’s the latest point spread and total for Sunday’s game.

Week 7 — Colts vs. Titans Stats to Know 

(Use the FTN Bets Prop Shop to find the best odds for player prop bets)

• Titans are 4-0 straight up and ATS against the Colts in their last four meetings, averaging 32.0 points per game
• Titans are 3-0 straight up and ATS in the last three games
• Colts are 3-1 straight up and ATS in the last four games
• Titans are 4-0 straight up after a regular-season bye under Mike Vrabel
• Colts are 1-5 to the over
• Titans lead the league in red-zone touchdown percentage (92.3%)
• Titans are 31st in opponents’ yards per play (6.3) and 28th in yards per game allowed (390.8)
• Colts have given up six points in the fourth quarter this season
• Colts are tied for the second-worst turnover differential (-5)
• Matt Ryan is second in passing yards per game (294.2)
• Ryan Tannehill has fewer than 182 passing yards in three of five games
• Michael Pittman has more than 120 receiving yards in two of his last five games
• Robert Woods has between 30 and 39 receiving yards in three of the last four games
• Deon Jackson is averaging 52.0 rushing yards and 54.0 receiving yards in the last two games
• Derrick Henry is averaging 100.3 rushing yards in the last three games