The Read Option: Fantasy Football Game-by-Game Breakdown (Week 16)

Welcome to The Read Option, FTN Fantasy’s NFL Week 16 game-by-game previews. This landing page will serve as your quarterback for the week and will link to preview for the upcoming slate of games.

FTN’s game-by-game previews are the most detailed and data-rich in the industry. This page will be updated throughout the week as the previews are published. Make sure to check back periodically as games are added.

Week 16 NFL Fantasy Football Game Previews

New Orleans Saints @ Los Angeles Rams

8:15 p.m. ET Thursday, Amazon Prime (announcers: Al Michaels and Kirk Herbstreit)
LAR -4.5, O/U 46.5
Pace: NO: 26.0 sec/snap (7th), LAR: 27.3 sec/snap (18th)

Derek Carr tossed three touchdowns last week, but I’m sure he and the Saints would love to have Chris Olave back in the lineup.

Click here to check out the full Saints/Rams Week 16 fantasy football breakdown! (free!)

Cincinnati Bengals @ Pittsburgh Steelers

4:30 p.m. ET Saturday, NBC (announcers: Noah Eagle and Todd Blackledge)
CIN -1.5, O/U 37
Pace: CIN: 26.5 sec/snap (13th), PIT: 27.9 sec/snap (28th)

Mason Rudolph will start at QB for the Steelers, while the Bengals offense could be without Ja’Marr Chase.

Click here to check out the full Bengals/Steelers Week 16 fantasy football breakdown!

Buffalo Bills @ Los Angeles Chargers

8 p.m. ET Saturday, Peacock (announcers: Mike Tirico and Cris Collinsworth)
BUF -11.5, O/U 44
Pace: BUF: 25.7 sec/snap (3rd), LAC: 25.8 sec/snap (4th)

Buffalo has found a rushing attack, and they have a great matchup to keep it going Saturday.

Click here to check out the full Bills/Chargers Week 16 fantasy football breakdown!

Indianapolis Colts @ Atlanta Falcons

1 p.m. ET Sunday, FOX (announcers: Adam Amin and Mark Schlereth)
ATL -1, O/U 44
Pace: IND: 23.1 sec/snap (1st), ATL: 26.3 sec/snap (10th)

The Colts are really banged up on offense right now. Michael Pittman and Zack Moss left last week’s game, while Jonathan Taylor continues to work his way back from a thumb injury.

Click here to check out the full Colts/Falcons Week 16 fantasy football breakdown!

Cleveland Browns @ Houston Texans

1 p.m. ET Sunday, CBS (announcers: Ian Eagle and Charles Davis)
CLE -1, O/U 41
Pace: CLE: 25.8 sec/snap (4th), HOU: 25.2 sec/snap (2nd)

We’ll see if C.J. Stroud and/or Nico Collins are able to return to Houston’s lineup this weekend.

Click here to check out the full Browns/Texans Week 16 fantasy football breakdown!

Green Bay Packers @ Carolina Panthers

1 p.m. ET Sunday, FOX (announcers: Chris Myers and Robert Smith)
GB -4.5, O/U 36.5
Pace: GB: 27.6 sec/snap (22nd), CAR: 28.4 sec/snap (29th)

We’ll have to keep an eye on the Green Bay wideouts. Christian Watson has been out with a hamstring issue, but now Jayden Reed is dealing with a toe injury.

Click here to check out the full Packers/Panthers Week 16 fantasy football breakdown!

Detroit Lions @ Minnesota Vikings

1 p.m. ET Sunday, FOX (announcers: Kenny Albert and Jonathan Vilma)
DET -3, O/U 47
Pace: DET: 27.0 sec/snap (17th), MIN: 26.3 sec/snap (10th)

The Lions bounced back in a huge way last week, scoring 42 points. We’ll see what they can do on the road against a division rival.

Click here to check out the full Lions/Vikings Week 16 fantasy football breakdown!

Seattle Seahawks @ Tennessee Titans

1 p.m. ET Sunday, CBS (announcers: Andrew Catalon, Tiki Barber and Matt Ryan)
SEA -2.5, O/U 41.5
Pace: SEA: 26.0 sec/snap (8th), TEN: 29.1 sec/snap (31st)

With Will Levis dealing with a high ankle sprain, we could see Ryan Tannehill back at quarterback for the Titans Sunday.

Click here to check out the full Seahawks/Titans Week 16 fantasy football breakdown!

Washington Commanders @ New York Jets

1 p.m. ET Sunday, CBS (announcers: Spero Dedes and Adam Archuleta)
NYJ -3, O/U 37.5
Pace: WAS: 27.7 sec/snap (24th), NYJ: 25.9 sec/snap (6th)

After being benched for Jacoby Brissett Sunday, Sam Howell isn’t a lock to start at quarterback for Washington.

Click here to check out the full Commanders/Jets Week 16 fantasy football breakdown!

Jacksonville Jaguars @ Tampa Bay Buccaneers

4:05 p.m. ET Sunday, CBS (announcers: Kevin Harlan and Trent Green)
TB -1, O/U 43
Pace: JAC: 27.5 sec/snap (21st), TB: 26.6 sec/snap (14th)

Trevor Lawrence is currently in the concussion protocol for Jacksonville.

Click here to check out the full Jaguars/Buccaneers Week 16 fantasy football breakdown!

Arizona Cardinals @ Chicago Bears

4:25 p.m. ET Sunday, FOX (announcers: Kevin Kugler and Mark Sanchez)
CHI -4.5, O/U 44
Pace: ARI: 27.3 sec/snap (18th), CHI: 28.5 sec/snap (30th)

Although it is a good matchup, the Bears continue to use all three running backs, making this a spot to potentially avoid for fantasy.

Click here to check out the full Cardinals/Bears Week 16 fantasy football breakdown!

Dallas Cowboys @ Miami Dolphins

4:25 p.m. ET Sunday, FOX (announcers: Kevin Burkhardt and Greg Olsen)
MIA -1.5, O/U 51
Pace: DAL: 26.0 sec/snap (7th), MIA: 27.8 sec/snap (26th)

Tyreek Hill was close to playing last week, so I would imagine he’ll return to the lineup Sunday.

Click here to check out the full Cowboys/Dolphins Week 16 fantasy football breakdown! (free!)

New England Patriots @ Denver Broncos

8:15 p.m. ET Sunday, NFL Network (announcers: Rich Eisen and Kurt Warner)
DEN -6.5, O/U 34.5
Pace: NE: 26.8 sec/snap (16th), DEN: 27.8 sec/snap (26th)

If Rhamondre Stevenson (ankle) remains sidelined, we’ll see if Ezekiel Elliott can bounce back in a great matchup.

Click here to check out the full Patriots/Broncos Week 16 fantasy football breakdown!

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Las Vegas Raiders @ Kansas City Chiefs

1 p.m. ET Monday, CBS (announcers: Jim Nantz and Tony Romo)
KC -10, O/U 41.5
Pace: LV: 27.6 sec/snap (22nd), KC: 26.7 sec/snap (15th)

It sounds like Isiah Pacheco will return for Kansas City, while Josh Jacobs could be back for the Raiders.

Click here to check out the full Raiders/Chiefs Week 16 fantasy football breakdown!

New York Giants @ Philadelphia Eagles

4:30 p.m. ET Monday, FOX (announcers: Joe Davis and Daryl Johnston)
PHI -11.5, O/U 42.5
Pace: NYG: 27.7 sec/snap (24th), PHI: 27.3 sec/snap (18th)

The Eagles have now lost three games in a row, but a home matchup against the Giants could be a get-right spot for this team.

Click here to check out the full Giants/Eagles Week 16 fantasy football breakdown!