Oakland A's left-hander Alex Wood will be in search of better results as he takes on the hosting Cleveland Guardians on Saturday. The club's Opening Day starter, Wood was tagged for six earned runs in that outing and has pitched to a 8.10 ERA through his first four starts of the season. He lasted just 4 1/3 frames his last time out, yielding four earned runs on seven hits, including a homer, with four walks and four strikeouts in a no-decision against the Washington Nationals. Wood has struggled with his control via an 11.8% BB% while his ground-ball rate has plummeted to just 32.7%. However, his results should improve once his bloated .442 BABIP normalizes.

Los Angeles Angels shortstop Zach Neto is on the bench to start Saturday's contest against the hosting Cincinnati Reds and right-hander Graham Ashcraft. Neto's slow start to the season continued in on Friday as he went 0-for-3 with a pair of strikeouts as part of a 7-1 loss in the series opener. The 23-year-old is hitting just .185 without a homer and four stolen bases alongside a .495 OPS across his first 72 plate appearances on the young season. Neto needed just 48 minor-league games before making his MLB debut last season when he hit .225 with nine homers, five steals, and a .685 OPS across 84 contests. Luis Rengifo will handle shortstop duties on Saturday.

Cleveland Guardians second baseman Andres Gimenez is not in the starting lineup for Saturday's contest against the visiting Oakland Athletics. The 25-year-old went 1-for-4 with a run scored, two RBI, and a stolen base during Friday's 10-2 victory but will begin Saturday's game on the bench. Gimenez has shown a nice combination of power and speed over the last couple of seasons, slugging 32 homers and stealing 50 bags over the last two campaigns. He has hit .291 on the young season and while he has yet to hit a home run, he does have three stolen bases and a .736 OPS across his first 91 trips to the plate. The Guardians are off to a hot start, sitting atop the AL Central with a 14-6 record on the young season.

San Francisco Giants third baseman Matt Chapman is not in the starting lineup for Saturday's afternoon contest against the visiting Arizona Diamondbacks and right-hander Zac Gallen. Chapman did his part on Friday by going 1-for-3 with a double and a walk but his team was blown out to the tune of a 17-1 final score as the Giants mustered just four hits on the night. The 30-year-old has flashed some power with four homers and five doubles on the young season but is also hitting just .205 with a .677 OPS across his first 90 trips to the plate in a Giants uniform. The Giants are just 9-12 on the young season despite a busy offseason that saw them add a number of notable free agents, including Chapman.

Arizona Diamondbacks catcher Gabriel Moreno is on the bench for Saturday's game against the San Francisco Giants and left-hander Kyle Harrison. Moreno started and went 2-for-3 with a walk, a double, two runs, and three RBI as part of a massive 17-1 blowout win over the Giants but will get a break in a day game following a night game on Friday. The young backstop is hitting .241 without a homer on the season but his impressive 14.3% BB% is roughly double his tiny 7.9% K% across his first 63 trips to the plate on the young season. Moreno has dealt with a thumb injury that cost him a couple of starts earlier in the week but he is back to health and is a batting average-first fantasy asset.