San Francisco 49ers DVOA, Stats, & NFL Rankings

Los Angeles Rams wide receiver Demarcus Robinson has taken over the team's WR3 role and has been a vital part of the offense. From weeks 12-16, Robinson averaged 64 receiving yards per game and scored a touchdown in four of five games. While Puka Nacua and Cooper Kupp remain the primary targets for Matthew Stafford, Robinson has built a strong connection with the veteran QB as well. Facing a Detroit Lions on Sunday that has allowed the third-most fantasy points to wide receivers, the 29-year-old is an intriguing DFS play.

San Francisco 49ers running back Christian McCaffrey (calf) will not practice this week, but head coach Kyle Shanahan expects CMC back at practice next week when the team starts making final preparations for the Divisional Round. The best running back in football suffered a mild right-calf strain in Week 17 and was held out as a precaution in a meaningless Week 18 regular season finale against the Los Angeles Rams last weekend. With a bye in the first round of the playoffs as the top seed in the NFC, the Niners are expecting McCaffrey to be ready for the Divisional Round against an opponent yet to be determined. Regardless of which team travels to San Francisco to take on the 49ers, McCaffrey is going to be the highest-priced RB for DFS lineups next weekend.

San Francisco 49ers wide receiver Brandon Aiyuk played a partial game in the team's 21-20 home loss to the Los Angeles Rams on Sunday. With San Francisco already locked into the No. 1 seed in the NFC playoffs, Aiyuk saw his last action of the game in the second quarter. Before he was pulled, Aiyuk secured three of four targets for 25 yards receiving. He finishes the best fantasy year of his career with 75 receptions for 1,342 yards and seven touchdowns. He'll likely be taken as a high-end WR2 in drafts this fall.

San Francisco 49ers tight end George Kittle (back spasms) and linebacker Dre Greenlaw (Achilles) have both been ruled out for the remainder of Week 18 versus the Los Angeles Rams. Both players were technically active this week but will not play. Neither player was in full uniform as Sunday's game kicked off. None of this news comes as a surprise given that San Francisco has clinched the NFC's No. 1 seed and has no reason to jeopardize the health of its key starters. Charlie Woerner will step up as the Niners' top tight end while Dee Winters takes over at weakside linebacker. Neither of them are on the fantasy radar.

San Francisco 49ers wide receiver Ray-Ray McCloud III (rib) and fullback Kyle Juszczyk (illness) are active for Week 18 versus the Los Angeles Rams. Both players had been listed as questionable. McCloud was limited in practice all week long, while Juszczyk was a late addition on Saturday. Fantasy managers shouldn't rely on either player this Sunday, though McCloud could sneak onto the fantasy radar if the 49ers limit snaps for Brandon Aiyuk and Deebo Samuel.