Baltimore Orioles outfielder Cedric Mullins and infielder Jorge Mateo are both sitting out of the lineup on Saturday against the Chicago White Sox. Kyle Stowers will draw into the lineup in left field and will hit eighth, while Ramon Urias will play third base and bat ninth against White Sox right-hander Erick Fedde. Rookie Colton Cowser shifts over to center field and will hit sixth in the batting order. Mullins' fantasy stock continues to fall after going hitless on Friday to drop his season line to .195/.242/.336, although he does have six home runs, 20 RBI and 10 stolen bases in 149 at-bats for the O's. Stowers has only played in seven games in his third big-league season in 2024 and has gone 2-for-8 with an RBI and three strikeouts. He represents a low-upside DFS option near the bottom of the Baltimore batting order on Saturday.

The Chicago White Sox reinstated rookie infielder Bryan Ramos (quadriceps) from the 10-day injured list on Saturday and optioned outfielder Zach DeLoach to Triple-A Charlotte in a corresponding move. Ramos, the team's No. 5 prospect per MLB Pipeline, is starting at third base and is batting sixth for the White Sox in his return from the IL on Saturday against the visiting Baltimore Orioles and right-hander Albert Suarez. The 22-year-old is returning from a mild left-quadriceps strain and should continue to play regularly moving forward for the rebuilding White Sox. In his first 10 contests in the big leagues, the Cuban infielder has held his own, going 9-for-32 (.281), although he has yet to hit his first home run. In two minor-league rehab starts with Charlotte, he went 2-for-4 with a run scored and two walks.

The Tampa Bay Rays placed outfielder Josh Lowe (oblique) on the 10-day injured list (retroactive to May 23) on Saturday with a right-oblique strain and reinstated right-hander Chris Devenski (knee) from the 15-day injured list in a corresponding move. It will be the second time this year already that Lowe has been put on the IL, and fantasy managers should expect him to miss more than 10 days given the nature of his injury. The 26-year-old left-handed hitter left Wednesday's game early against the Boston Red Sox with right-side tightness, and an MRI exam on Thursday showed a dreaded oblique strain. Lowe's power/speed upside makes him worth stashing in all fantasy formats again while he's hurt. In the meantime, the biggest beneficiary in Tampa's outfield with Lowe hurt will most likely be Jonny DeLuca.

Milwaukee Brewers left-hander Jared Koenig is serving as the opener against the Boston Red Sox at Fenway Park on Saturday for the second straight day. Koenig will be followed by starter Colin Rea this time around. Koenig joins Zack Greinke as the only Brewers pitchers to start consecutive games. In his "start" in Friday's series opener in Beantown, Koenig allowed a hit and a walk and struck out one in two-thirds of an inning before giving way to right-hander Bryse Wilson. The 30-year-old southpaw won't go very long again in Saturday's contest and isn't a realistic fantasy streaming option. Rea, meanwhile, will still be worth considering as a deep-league streamer despite not actually starting this game. In his nine starts for the Brew Crew this year, he's gone 3-2 with a solid 4.07 ERA (4.67 FIP) and 1.39 WHIP while walking 17 and striking out 35 in 48 2/3 innings.

When asked if relief pitcher Edwin Diaz could receive a ninth-inning opportunity on Saturday against the visiting San Francisco Giants, New York Mets manager Carlos Mendoza said, "He's our closer." However, Mendoza also referred to Diaz as "one of our options" and said "we'll piece it together." This comes after the skipper recently said last Sunday that Diaz's bullpen role would be more "fluid" given his recent struggles. The 30-year-old flamethrower allowed a season-high four earned runs on four hits (one homer) in just one-third of an inning last weekend but struck out two in a scoreless inning on Friday against the Giants for his second hold of the year. Diaz has already blown three saves in 2024 and hasn't recorded a save since May 6, but the Mets could work him back into the role if he can settle down and stack a few more good outings together.