Chicago White Sox outfielder Luis Robert Jr. (rib cage) is dealing with some soreness in his rib-cage area and is out of the starting lineup on Friday against the division-rival Detroit Tigers at Comerica Park. The injury isn't considered serious, though, and he could return on Saturday for the second game of the series. Dominic Fletcher will make the start in center field on Friday and will hit ninth for the Pale Hose against Tigers right-hander Brenan Hanifee. Fletcher will be a deep DFS sleeper to avoid on Friday, as the 27-year-old outfielder has gone 44-for-212 (.208) on the year with just one home run and 16 RBI. After making his first All-Star appearance in 2023, Robert has hit a career-low .227 (88-for-388) this year. He has managed a career-high 22 stolen bases while also contributing 14 home runs and just 36 RBI for a terrible White Sox team.

Pittsburgh Pirates infielder/outfielder Oneil Cruz and third baseman Jared Triolo are both out of the lineup for Friday's series finale against the New York Yankees in the Bronx. Billy Cook will get the start in center field and will bat in the nine-hole, with Isiah Kiner-Falefa manning third base and batting sixth against Yankees left-hander Carlos Rodon. Kiner-Falefa has one hit in three career at-bats versus Rodon. The 25-year-old Cruz will get a day of rest against a southpaw pitcher. The Dominican has hit just .227 (32-for-141) against lefties this year with six of his 21 home runs on the season. Cruz recently made the full-time transition from shortstop to center field in Pittsburgh and has also reached the 20-20 milestone for the first time in 2024 in his fourth year in the big leagues. Cruz enters play on Friday slashing .263/.325/.456 with a .781 OPS, 21 homers, 76 RBI and 22 thefts in 143 games.

Toronto Blue Jays rookie outfielder Joey Loperfido is not in the team's starting lineup for Friday's series opener at the Rogers Centre against the visiting Miami Marlins. With Loperfido starting on the bench, fellow outfield prospect Jonatan Clase is starting in center field and is batting eighth against Marlins right-hander Adam Oller. Loperfido, 25, has appeared at both center field and left field for Toronto and has mostly struggled offensively since being acquired from the Houston Astros at the trade deadline in the deal that sent lefty Yusei Kikuchi to Houston. Loperfido has gone 27-for-130 (.208) with two homers, eight RBI, two steals and 48 strikeouts in his 41 games in Toronto. Clase, who was also acquired via trade with the Mariners this year, will be playing in just his sixth game with the Jays. So far, he's gone 6-for-12 with a homer, double and two RBI in 14 plate appearances.

Tampa Bay Rays outfielder Christopher Morel and shortstop Taylor Walls are getting the day off on Friday for the series opener against the division-rival Boston Red Sox at Fenway Park. Richie Palacios is making the start in left field and is hitting seventh, with Jose Caballero returning to shortstop and batting eighth against Red Sox right-hander Nick Pivetta. Morel has reached the 20-homer mark for the second straight season, but he's also hitting under .200 in 149 combined games with the Rays and Chicago Cubs. He's been even worse since coming to Tampa at the trade deadline, hitting .183 (30-for-164) with just three home runs, four doubles, two triples, seven RBI and 55 strikeouts in 180 trips to the plate. Palacios has mainly been a speed threat for fantasy managers in AL-only leagues with a career-high 19 stolen bases in 2024, but he hasn't provided much else in just 90 games.

Houston Astros shortstop Jeremy Pena and outfielder Jason Heyward will both start on the bench for Friday's series opener in Cleveland against the Guardians at Progressive Field. Grae Kessinger is starting at the 6 and batting ninth, while Mauricio Dubon is in left field and batting eighth against Guardians rookie left-hander Joey Cantillo. Pena doesn't sit often, as this is his first day off since Aug. 22. Kessinger made his big-league debut last year and played in 26 games, hitting .200 (8-for-40) with a homer and an RBI. He's only played in 20 games in 2024 and has gone hitless in 17 plate appearances with one walk and five strikeouts. DFS gamers should ignore him on Friday. Dubon, a super-utility man for the Astros, has very little DFS sleeper appeal at the bottom of the order with just four home runs and 47 RBI in 394 at-bats in 2024.