San Francisco 49ers DVOA, Stats, & NFL Rankings

San Francisco 49ers rookie running back Isaac Guerendo (foot) will undergo an MRI exam on Monday after potentially spraining his foot in Week 14. With Christian McCaffrey (knee) and Jordan Mason (ankle) sidelined, the 24-year-old took over in the backfield in Sunday's win over the Bears. He played well, amassing 78 yards and two scores off 15 carries and adding 50 yards off two receptions. It was a spirited performance for those that picked Guerendo up off the waiver wire and started him this week, but the elation was short-lived. If he can't suit up in Week 15 versus the Rams, Patrick Taylor Jr., who had 25 yards and a touchdown off seven attempts against Chicago, will likely handle the starting duties and will be a popular waiver-wire addition.

San Francisco 49ers running back Isaac Guerendo (foot) is questionable to return to Sunday's matchup versus the Bears. With Christian McCaffrey (knee) and Jordan Mason (ankle) on the shelf, Guerendo took over as the team's top option out of the backfield. He has played well, too, running for 78 yards and two scores off 15 carries, adding two grabs for 50 yards. If the 24-year-old doesn't return, Patrick Taylor Jr., who already has a touchdown, will likely continue to lead the way.

Despite a season that hasn't gone as planned in 2024, the San Francisco 49ers still plan to lock in quarterback Brock Purdy on a long-term extension for 2025 and beyond this offseason. Injuries have mostly been to blame for San Fran's 5-7 record, as their offensive line has endured some key injuries, while receiver Brandon Aiyuk (knee) and All-Pro running back Christian McCaffrey (knee) have both missed the majority of the season due to injuries. Despite the injuries to key offensive players around him, Purdy ranks eighth in the NFL in EPA per play at the QB position and has thrown for 2,707 yards, 13 touchdowns and eight interceptions in his 11 starts. He should be viewed as a low-end QB1 option in fantasy this Sunday against the Chicago Bears. Purdy's 21.7 average fantasy points per game has him tied for eighth among QBs with Russell Wilson.

San Francisco 49ers rookie wide receiver Ricky Pearsall should not be started in any formats in Week 14 when he faces the Chicago Bears. The former first-round selection has seen three targets over the past three games but has been unable to come down with any of them. However, during Weeks 7 through 10, the Florida product averaged a modest 11.4 PPR points per game. While Pearsall is deployed as the clear No.3 wide receiver, he has been unable to find much consistency in the passing attack behind Deebo Samuel Sr., Jauan Jennings, and tight end George Kittle. However, with Christian McCaffrey (knee) and Jordan Mason (ankle) sidelined, the 49ers may rely on their passing attack more often down the stretch. However, given his lack of production over the past month, fantasy managers should not consider starting him for the foreseeable future.

San Francisco 49ers running back Jordan Mason (ankle), who still hasn't been placed on Injured Reserve, was officially ruled out for the Week 14 game against the Chicago Bears this Sunday after missing practice all week. Mason suffered a high-ankle sprain in last Sunday night's loss to the Buffalo Bills and is expected to eventually land on IR, which would require him to miss at least four games. The 25-year-old will likely go on IR before the deadline on Saturday, which will make him eligible to return for the Week 18 regular-season finale against the division-rival Arizona Cardinals. With fantasy championships typically coming in Week 17, Mason should have already been dropped in redraft leagues. With Christian McCaffrey (knee) also done for the season, rookie Isaac Guerendo is now the 49ers' lead back, and he'll have immediate RB2 upside in his first NFL start this Sunday versus Chicago.