Los Angeles Chargers vs. Jacksonville Jaguars – Week 3 Betting Preview

The Jacksonville Jaguars will travel across the country to take on the Los Angeles Chargers in Week 3. The Jags are coming off a 24-0 shutout against the Indianapolis Colts, one of the franchise’s most impressive wins in recent memory and will be tested again by a well-rounded Chargers team.

The Chargers had a little extra time to prepare for the upstart Jaguars after a tough loss to the Chiefs on Thursday Night Football. A backbreaking 99-yard pick-six all but sealed Los Angeles’ fate last week, and Kansas City added injury to insult as quarterback Justin Herbert suffered a rib fracture later in the game.

Herbert is trending in the right direction and it’s possible, too, that wide receiver Keenan Allen suits up after missing last week’s contest with a hamstring injury, so the Chargers could be back at full strength for this showdown with Jacksonville.

When is Los Angeles Chargers vs. Jacksonville Jaguars Week 3?

Date/Time: Sunday, Sept. 25, 4:05 p.m. ET
Stadium: SoFi Stadium
How to Watch: CBS, Paramount+
Opening Odds: Chargers -10 | O/U 50.5

Week 3 Chargers vs. Jaguars Betting Odds

Here’s a look at the latest point spread and total for Sunday’s game.

Week 3 Chargers vs. Jaguars Stats to Know

• The Chargers are 5-4 ATS in their last nine games as home favorites, including Week 1 against the Raiders
• The Jaguars are 2-6 ATS in their last eight games as road underdogs
• Justin Herbert’s is averaging 314 passing yards in his last five games
• Trevor Lawrence’s O/U is 247.5 passing yards – he’s gone over that number in five of 19 career games
• Austin Ekeler’s O/U is 50.5 rushing yards – he’s averaging 59 yards in the Chargers’ last 12 games as favorites
• Christian Kirk’s O/U is 60.5 receiving yards – he’s gone over that number in both of his games as a member of the Jaguars
• Mike Williams is averaging 2.5 more receptions and 19 more yards per game without Keenan Allen in the lineup since 2021