Pittsburgh Steelers vs. Cincinnati Bengals – Week 1 Betting Preview

The Pittsburgh Steelers visit the Cincinnati Bengals in a key divisional matchup to start the 2022 season. The Bengals are the biggest home betting favorites on the Week 1 schedule.

The reigning AFC North champions, Cincinnati is expected to contend for a playoff spot. That’s not exactly the case for Pittsburgh, which named Mitch Trubisky as its Week 1 starting quarterback. Trubisky rode the bench in Buffalo for the entirety of the 2021 season. Joe Burrow emerged as one of the NFL’s best quarterbacks and led the Bengals to the Super Bowl in his second season.

Let’s take a look at some key statistics and information about this matchup.

When is Pittsburgh Steelers vs. Cincinnati Bengals Week 1? 

Date/Time: Sept. 11, 1 p.m. ET 
Arena: Paycor Stadium 
How to watch: CBS
Opening odds: Bengals -6.5 | CIN -250, PIT +200 | O/U 45 

Week 1 Steelers vs. Bengals Betting Odds 

Here’s the latest point spread and total for Sunday’s game.

Week 1 — Steelers vs. Bengals Stats to Know

(Use the FTN Bets Prop Shop to find the best odds for player prop bets)

• Bengals are 4-1 straight up and ATS in their last five games as favorites
• Steelers have lost one season opener since 2016
• Steelers won straight up in Week 1 last season as a 6.5-point underdog
• The last four meetings between Pittsburgh and Cincinnati have been decided by at least 10 points
• Joe Burrow’s over/under is 255.5 passing yards — he’s thrown for no more than 213 yards in three career games against Pittsburgh
• Steelers have held four of the last five opposing quarterbacks to 216 yards or fewer 
• Mitch Trubisky’s over/under is 225.5 passing yards — he’s gone over that total in five of his last six starts
• Ja’Marr Chase’s over/under is 71.5 receiving yards — he’s gone under that total in seven of the last 10 regular-season games
• Joe Mixon’s over/under is 69.5 rushing yards — Pittsburgh gave up a league-high 146.1 rushing yards per game last season
• Najee Harris’ over/under is 58.5 rushing yards — he’s gone over that total in 10 of the last 14 games