Philadelphia Eagles vs. Arizona Cardinals – Week 5 Betting Preview

The Philadelphia Eagles look to maintain their perfect record when they visit the Arizona Cardinals in Week 5. The Eagles are significant road favorites after dominating their opponents for the first month of the 2022 NFL season.

Philadelphia has the best odds to represent the NFC in the Super Bowl, winning four games by an average of 11 points per contest. Arizona is 2-2, managing to tread water during DeAndre Hopkins’ suspension. An upset over the Eagles would be the Cardinals’ most impressive win of the year, by far. 

Let’s take a look at some key statistics and information about this matchup.

When is Philadelphia Eagles vs. Arizona Cardinals Week 5? 

Date/Time: Oct. 9, 4:25 p.m. ET 
Arena: State Farm Stadium
How to watch: FOX
Opening odds: Eagles -6 | PHI -240, AZ +200 | O/U 49.5

Week 5 Eagles vs. Cardinals Betting Odds 

Here’s the latest point spread and total for Sunday’s game.

Week 5 — Eagles vs. Cardinals Stats to Know 

(Use the FTN Bets Prop Shop to find the best odds for player prop bets)

• Eagles have won three straight games ATS
• Cardinals are 0-2 straight up at ATS at home
• Cardinals and Eagles have both gone under the total in two games
• Eagles have led by at least 15 points in every fourth quarter
• Cardinals haven’t beaten a team that has more than one win
• Eagles are second in yards per game (435.5) and fourth in points per game (28.8)
• Eagles have given up three total offensive touchdowns in the last three games 
• Cardinals and Eagles are tied for fewest turnovers (2)
• Eagles are first in turnover differential (+8)
• Jalen Hurts is averaging 280.0 passing yards and 51.3 rushing yards per game
• Kyler Murray has at least 277 passing yards in two of the last three games
• A.J. Brown is third in receiving yards per game (101.0)
• Marquise Brown is averaging 98.7 receiving yards in the last three games
• Miles Sanders is third in rushing yards per game (89.0)
• James Conner doesn’t have more than 55 rushing yards in any game this season