Minnesota Vikings vs. Buffalo Bills – Week 10 Betting Preview


Based on team records, the best Week 10 matchup is Sunday’s game between the Minnesota Vikings and Buffalo Bills. The Bills are the AFC’s No. 1 seed at the midway point of the 2022 season. The Vikings are the NFC ‘s No. 2 seed and running away with first place in the division.


Josh Allen’s elbow injury is hanging over the game in Buffalo. If the MVP candidate is forced to miss Sunday’s contest, the betting line could move dramatically toward Minnesota. The Vikings have only been beaten by the undefeated Philadelphia Eagles.

Let’s take a look at some key statistics and information about this matchup.

When is Minnesota Vikings vs. Buffalo Bills Week 10? 

Date/Time: Nov. 13, 1 p.m. ET 
Arena: Highmark Stadium, Buffalo
How to watch: FOX
Opening odds: Bills -7.5 | MIN +280, BUF -340 | O/U 48.5

Week 10 Vikings vs. Bills Betting Odds 

Here’s the latest point spread and total for Sunday’s game.


Week 10 — Vikings vs. Bills Stats to Know 

(Use the FTN Bets Prop Shop to find the best odds for player prop bets)

  • Bills are 3-0 straight up and 2-1 ATS at home
  • Vikings are 6-0 straight up and 2-3-1 ATS in the last six games
  • Bills are first in yards per play (6.5) and yards per game (416.4)
  • Vikings have scored at least 20 points in six straight games
  • Bills haven’t given up more than 21 points in any game
  • Bills are first in points per game allowed (14.8)
  • Vikings are 27th in passing yards allowed per game (256.9)
  • Bills have outscored opponents 106-27 at home
  • Bills are last is turnover percentage (17.1%)
  • Josh Allen has exactly two interceptions in two straight games
  • Kirk Cousins has exactly two passing touchdowns in three straight games
  • Stefon Diggs is third in receiving yards per game (107.1)
  • Justin Jefferson has at least 98 receiving yards in five straight games
  • Devin Singletary is averaging 43.4 rushing yards per game
  • Dalvin Cook is averaging 76.0 rushing yards per game
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