Las Vegas Raiders vs. Los Angeles Chargers – Week 1 Betting Preview


In a rematch of 2021’s regular season finale, the Los Angeles Chargers will host the Las Vegas Raiders in what projects to be an explosive offensive game. The Chargers have Super Bowl aspirations this year despite missing the playoffs last season at the hands of the Raiders, but both of these AFC West foes have both made big offseason moves. They’ll look to start off on the right foot in a division that oddsmakers project to be the league’s best.


When is Los Angeles Chargers vs. Las Vegas Raiders Week 1?

Date/Time: Sunday, Sept. 11, 4:25 p.m. ET
Stadium: SoFi Stadium
How to Watch: CBS, Paramount+
Opening Odds: Chargers -4 | O/U 52.5

Week 1 Chargers vs. Raiders Betting Odds

Here’s a look at the latest point spread and total for Sunday’s game.


Opening Odds – Chargers vs. Raiders

The Chargers opened as 4-point favorites in May, and the spread has only gotten as low as -3.5. With revenge on their minds, the Chargers went out and upgraded a defense that allowed Las Vegas to score 35 points in a fate-deciding win in Week 18 last year. Los Angeles added edge rusher Khalil Mack to pair with Joey Bosa, and it added star cornerback J.C. Jackson to bolster the secondary, but he won’t be available in Week 1.

The total has bounced between 51.5 and 52.5 for this matchup of high-flying offenses. The Raiders added Derek Carr’s former college teammate – Davante Adams – to a skill group that already consisted of talents like Josh Jacobs, Hunter Renfrow and Darren Waller.

Week 1 Chargers vs. Raiders Stats to Know

  • The Chargers and the Raiders went 8-9 ATS in 2021
  • Chargers are 4-4 ATS in last eight games as home favorites
  • Raiders are 7-4 AT in last 11 games as underdogs
  • Raiders are 4-2 ATS in last six games as road underdogs
  • The Chargers and Raiders went 1-1 straight up and ATS against each other last season
  • The OVER has hit in four straight Chargers home games
  • Justin Herbert’s O/U is 281.5 passing yards – he went over that number in 9 of 17 games in 2021
  • Derek Carr’s O/U is 264.5 passing yards – he’s failed to hit that number in six straight regular season games
  • Davante Adams’ O/U is 77.5 receiving yards – he’s gone over that number in six of his last eight regular season games
  • Keenan Allen’s O/U is 70.5 receiving yards – he’s failed to reach that number in four of his last five games
  • Austin Ekeler’s O/U is 99.5 rushing + receiving yards – he’s gone under that number in three of his last four games
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