Milwaukee Bucks guard Damian Lillard (calf) received some tough news on Tuesday and will be sidelined indefinitely. The star guard has been diagnosed with deep vein thrombosis in his right calf. That being said, Lillard won't be on the court anytime soon while he deals with blood clots in his right calf. Fantasy managers are probably safe to drop him with most leagues already in the playoffs. The expectation is that Ryan Rollins and Gary Trent Jr. will see boosts going forward. Between the two, Trent is the better fantasy option while Lillard is out.

Milwaukee Bucks forward/center Giannis Antetokounmpo (foot) has been listed as questionable for Wednesday's tilt against the Denver Nuggets. After battling a knee and calf issue throughout the season, Antetokounmpo is now on the injury report due to a left foot sprain. He may exit the lineup following 18 consecutive appearances. Damian Lillard (calf) is already out, so the Bucks would be in big trouble if Antetokounmpo also won't be available. Kyle Kuzma and Gary Trent Jr. would need to contribute more on the offensive end. The latter may take Antetokounmpo's spot in the starting unit, with Kuzma moving over to the power forward position.

Denver Nuggets center Nikola Jokic (ankle) will likely remain on the shelf for Wednesday's matchup against the Milwaukee Bucks, as the team lists him as doubtful on the injury report. This would mark his sixth consecutive absence due to an issue with his left ankle. DeAndre Jordan has started in the last two games Jokic has missed. The veteran has shown that he can still get the job done, averaging 10.5 points and 16.0 rebounds. However, Jordan may have a tougher time filling the stat sheet on Wednesday, as Milwaukee allows the fifth-fewest fantasy points in the league to opposing centers.

Boston Celtics forward Jayson Tatum (ankle) has been tagged as doubtful for Wednesday's matchup against Kevin Durant and the Phoenix Suns. The Celtics star sprained his left ankle on Monday against the Sacramento Kings, exiting the action after logging only 25 minutes. It appears he will miss at least one contest due to the injury. The rest of Boston's big guns are completely healthy heading into Wednesday, so we can expect Jaylen Brown, Derrick White, and Kristaps Porzingis to lead the offense. Al Horford is likely to step into the starting five if Tatum is ruled out.

Los Angeles Clippers guard James Harden (foot) is considered questionable for Wednesday's clash against the New York Knicks. He has appeared on the injury report due to a sore right foot sustained during Sunday's matchup against the Oklahoma City Thunder. If Harden is unable to play on Wednesday, it will mark only his fourth absence of the season. Derrick Jones Jr., Bogdan Bogdanovic, or Ben Simmons may replace Harden in the starting lineup. Meanwhile, Norman Powell and Kawhi Leonard would take on larger roles offensively, with Kris Dunn assuming additional playmaking duties.