Minnesota Timberwolves guard Mike Conley (hamstring) has been ruled out ahead of Saturday's game against the San Antonio Spurs. The veteran guard has now missed three of the last four games. Nickeil Alexander-Walker is expected to move into the starting five with Conley out. He'll be worth a look as a deep league streaming option. Jordan McLaughlin and Shake Milton should see additional minutes off the bench. However, neither of them will likely do enough to warrant streaming on Saturday.

Boston Celtics center Kristaps Porzingis (ankle) won't play in Saturday's game against the Los Angeles Clippers. The veteran tweaked his ankle in Thursday's 143-110 victory over the Miami Heat. Although the injury isn't anything serious, it will keep him off the floor for at least a game. Porzingis has averaged 19.5 points, 6.7 rebounds, and 1.8 blocks this season, so his absence is a tough blow for the Celtics. However, Al Horford should take his place in the lineup, with the 37-year-old averaging 9.2 points, 7.5 rebounds, and 1.1 blocks in 17 starts this season, making him a viable asset for fantasy managers.

Detroit Pistons guard Cade Cunningham (knee) finished with 20 points and 12 assists in Saturday's loss to the Washington Wizards. Cunningham returned after an eight-game absence because of a knee injury. Although he managed to amass a double-double, he shot a rough 7-for-17 from the field. The 22-year-old also had seven turnovers. At any rate, Cunningham played as well as expected in his first game in weeks. However, it remains to be seen if Cunningham will be back in the lineup on Sunday against OKC, the second of consecutive games. If he's not, Killian Hayes and Alec Burks would be in line for more work.

Los Angeles Clippers forward Paul George (groin) is questionable ahead of Saturday's game against the Boston Celtics. The veteran has been managing a groin injury and carried the same designation before Friday's win over the Toronto Raptors. However, he was on the floor, ending the night with 21 points, two blocks, and a steal. George logged just 28 minutes, which will help his chances of being active versus the Celtics. But if he doesn't suit up, Russell Westbrook, Norman Powell, and Kawhi Leonard could benefit from a statistical perspective.

Dallas Mavericks guard Kyrie Irving (thumb) is doubtful for Saturday's meeting with the Sacramento Kings. Irving will likely miss a third consecutive outing as the multi-time All-Star continues to deal with a sprained right thumb. Luka Doncic (ankle), coming off a 73-point outing on Friday against Atlanta, would normally absorb most of the scoring opportunities. However, with Doncic and Derrick Jones Jr. (wrist) questionable, fantasy managers could get extra production out of guys like Josh Green, Tim Hardaway Jr., and Dante Exum. There's also a chance Jaden Hardy could get enough work to warrant value consideration in DFS contests.