Philadelphia Phillies relief pitcher Jose Alvarado has been suspended for 80 games. The left-hander has tested positive for a performance-enhancing substance. According to Todd Zolecki of MLB.com, this suspension is effective immediately. Through the early part of the campaign, the left-hander has been a very effective option in the Philadelphia bullpen, holding a 2.70 ERA with a 1.20 WHIP. He has struck out 25 batters across 20 innings and tallied seven saves. The 29-year-old has generated a strong 2.77 xERA (86th percentile) and a 47.3% ground-ball rate (71st percentile). He has also shown a strong command of his pitches, tallying strikeouts at an elite 29.8% rate and serving walks at a 4.8% rate. While Alvarado is sidelined, fantasy managers should expect Jordan Romano to see most of the save opportunities in Philadelphia.

The Minnesota Twins have placed left-handed pitcher Danny Coulombe (forearm) on the 15-day injured list with a forearm strain. The 35-year-old has not appeared in a game since Wednesday. Through his first 16 2/3 innings of work this season, the left-hander has been one of the most effective relief pitchers in the sport. He has not allowed a run and posted a stellar 0.60 WHIP. He has struck out 19 batters and served up walks at an impressive 3.3% rate. Under the hood, he has generated a 1.69 xERA (100th percentile) and a .187 xBA (95th percentile). He has tallied two holds and two saves, pitching primarily in the seventh and eighth innings. While he is sidelined, fantasy managers should expect Jhoan Duran to serve as the primary closer, with Griffin Jax and Cole Sands being the primary setup options.

Tampa Bay Rays outfielder Chandler Simpson (hand) is dealing with a sore right hand. Ryan Bass of the FanDuel Sports Network reported that the young outfielder has his right hand wrapped. Fantasy managers should continue to monitor his status leading up to their next contest on Monday evening against the Houston Astros. Simpson suffered this injury during Saturday's contest when sliding into home plate. Through his first 25 games at the MLB level, the No. 7-ranked prospect in the Tampa Bay system has posted an impressive .301/.327/.344 slash line. Simpson has flashed his elite speed as he has swiped 11 bags. While he remains sidelined, fantasy managers should expect Kameron Misner and Jose Caballero to see most of the opportunities in center field.

The Baltimore Orioles have designated starting pitcher Kyle Gibson for assignment. Gibson has had a rough start to the campaign. Through his first 12 1/3 innings of work, the veteran right-hander has posted a hefty 16.78 ERA with a 2.92 WHIP. He has tallied just 10 punchouts and served up walks at a high 9.6% rate. In his most recent outing on Saturday against the Washington Nationals, Gibson tallied just two outs and allowed six hits, six runs, and one walk. Last season, the 37-year-old held his own with St. Louis, posting a 4.24 ERA with a 1.35 WHIP across 169 2/3 innings of work. However, given his disappointing start to the 2025 campaign, the struggling Orioles decided to cut ties with him. This could open a path for Charlie Morton or Keegan Akin to return to the rotation.

The Miami Marlins have activated infielder Otto Lopez (ankle) off the 10-day injured list prior to their contest against the Tampa Bay Rays on Sunday. In a corresponding move, the Marlins placed shortstop Xavier Edwards (back) on the 10-day injured list. Lopez has been kept out of action since May 2 with a Grade 2 right ankle sprain. Through his first 30 games of the campaign before his injury, Lopez posted a .229/.294/.330 slash line with five doubles, two home runs, three stolen bases, and a 17:10 K:BB. However, under the hood, Lopez has generated an elite .294 xBA, which suggests he should see positive regression when he returns to action. This afternoon, Lopez will get the start at the keystone and will bat in the seven-hole.