San Francisco 49ers DVOA, Stats, & NFL Rankings

San Francisco 49ers running back Patrick Taylor Jr. produced well filling in for rookie Isaac Guerendo (knee), who was carted off the field in the first quarter. The former Memphis Tiger took 17 carries for a career-high 109 yards and caught one of four targets for 12 yards through the air. Taylor Jr. looked much better on Sunday than in any other of his limited opportunities in 2024 with physical, one-cut running. The fact that he got any game time at all this year was an improbability in the preseason, as he had four running backs ahead of him on the depth chart before they all went down with injuries at various times. Taylor Jr. finishes the year with 39 carries for 183 yards and one touchdown. He'll be an unrestricted free agent this summer.

Per head coach Kyle Shanahan, San Francisco 49ers running back Isaac Guerendo (knee, ankle) has likely picked up an MCL sprain but will undergo more testing on Monday to confirm the severity of the injury. Matt Barrows of The Athletic reported the news. That'd be a best-case scenario for the rookie, who was carted off in the first quarter of his team's 47-24 loss to the Arizona Cardinals. Guerendo was bent up awkwardly not even two minutes into the contest and quickly ruled out afterward. San Francisco has been unable to keep a running back healthy this season, as they've had four suffer serious injuries. It's been a disappointing year for the 49ers -- a team with Super Bowl aspirations that won't make a playoff appearance in 2024 after a campaign riddled with injuries. They'll hope for better in 2025.

San Francisco 49ers wide receiver Jauan Jennings was disqualified from Sunday's meeting with the Arizona Cardinals. The wideout was having a fantastic game, amassing seven grabs (10 targets) for 52 yards before getting thrown out in the second quarter for a physical altercation with Cardinals cornerback Sean Murphy-Bunting. With the 49ers ending a disappointing season, Jennings will finish with career-highs in catches (77), targets (113), yards (975), and touchdowns (six). His stock heading into the 2025-26 campaign will already be higher than in previous years. However, if the Niners don't bring back Deebo Samuel Sr., it will increase even more.

San Francisco 49ers running back Isaac Guerendo (knee, ankle) exited during the first quarter of Sunday's Week 18 game against the Arizona Cardinals. He has been ruled out for the remainder of the contest. It was an ugly scene in Arizona as Guerendo's leg bent awkwardly while he was being tackled. He was in noticeable pain while being carted off the field, and the 49ers ruled him out with both knee and ankle injuries very quickly. He finishes Sunday's contest with two carries for five yards. All in all, he registered 420 rushing yards, 152 receiving yards, and four total touchdowns while splitting time as a depth option and starter this season. Patrick Taylor Jr. will lead the 49ers' backfield for the remainder of Sunday's contest.

San Francisco 49ers tight end George Kittle (ankle, hamstring) is officially active for Sunday's Week 18 contest against the Arizona Cardinals. He had been listed as questionable. Although the 49ers have already been eliminated from playoff contention, Kittle will be suiting up for the season finale. Quarterback Brock Purdy (elbow), however, won't play, which means Kittle will be catching passes from Joshua Dobbs. The 31-year-old ranks second among tight ends in fantasy points this season, and he enters the season finale as a high-end TE1.