San Francisco 49ers DVOA, Stats, & NFL Rankings

According to Cam Inman of the Bay Area News Group, San Francisco 49ers tight end George Kittle (ankle, hamstring) is listed as questionable for Sunday's game against the Arizona Cardinals. Kittle opened the week as a non-participant but was able to upgrade to limited participation on Thursday and Friday. Fantasy managers should continue to monitor his status over the weekend, as he may end up being a game-time decision. Kittle saw his typical workload on Monday evening and logged 56 offensive snaps and was able to bring in all eight of his targets for 112 yards. Even though Joshua Dobbs is slated to get the start, fantasy managers should still view Kittle as a TE1 without Brock Purdy (elbow) under center. He will be facing an Arizona defense that has allowed the fifth-fewest PPR points to opposing tight ends this season.

San Francisco 49ers general manager John Lynch said it was a medical decision to sit quarterback Brock Purdy (elbow) for the Week 18 regular-season finale against the division-rival Arizona Cardinals this Sunday and also downplayed the signal-caller's injury. "It's nothing more than when you hit your funny bone. When you get an NFL helmet in the wrong place it irritates the nerve. Brock is going to be fine. It's going to quiet down," Lynch said. The 25-year-old injured his elbow late in the Monday night loss to the Detroit Lions and hasn't practiced yet this week. With the Niners already eliminated from the playoffs, there's just no reason for the team to throw Purdy out there against Arizona. Veteran Joshua Dobbs will get the start instead. Entering Week 18, Purdy is the QB10 in overall fantasy points, although his 2024 was a step down from his breakout in 2023.

San Francisco 49ers rookie wide receiver Ricky Pearsall (chest, illness) was limited in practice on Thursday for the second straight day this week. If Pearsall cannot upgrade to full participation at Friday's practice, he could carry a questionable designation into the Week 18 regular-season finale on Sunday against the division-rival Arizona Cardinals. The first-rounder is coming off the best game of his rookie season in the Monday night loss to the Detroit Lions, when he set season-highs across the board in catches (eight), targets (10) and receiving yards (141) while catching his second touchdown of the year. There's a chance fellow wideout Deebo Samuel Sr. (ribs, wrist) doesn't play this weekend, which would thrust Pearsall into the WR2 role behind Jauan Jennings. However, with backup QB Joshua Dobbs getting the start, Pearsall would still be an unreliable, boom/bust WR4/5 in fantasy.

After being limited in practice on Wednesday, San Francisco 49ers tight end George Kittle (ankle, hamstring) upgraded to a full practice session on Thursday. Kittle is battling through multiple injuries with one final game left this year, but his ability to practice in full on Thursday means he should be able to gain clearance to play in the Week 18 regular-season finale on Sunday against the division-rival Arizona Cardinals. Although the 31-year-old's fantasy value will take a hit if he plays this weekend with quarterback Joshua Dobbs getting the start over Brock Purdy (elbow), Kittle will still be in play as a TE1 for lineups as the top-scoring TE in half-PPR scoring this year thanks to catching 76 of his 91 targets for 1,079 yards and a league-high eight TDs. If Kittle plays, he figures to be Dobbs' favorite target, especially if receiver Deebo Samuel Sr. (ribs, wrist) is held out.

San Francisco 49ers wide receiver Deebo Samuel Sr. (ribs, wrist) picked up his second straight DNP this week after not practicing with the team on Thursday. Samuel is dealing with multiple injuries following Sunday night's loss to the Detroit Lions in Week 17 and is now firmly up in the air to play this Sunday against the division-rival Arizona Cardinals in the Week 18 regular-season finale with nothing on the line for either team. Backup quarterback Joshua Dobbs has already been named the starter with Brock Purdy (elbow) likely to be shut down, so Samuel's already shaky fantasy value will take another hit if he actually suits up this weekend. The 28-year-old has scored in back-to-back weeks, but on Sunday night he only caught one pass for five yards and had three carries for 16 yards. Samuel will be a touchdown-dependent WR3/flex if he faces Arizona in the regular-season finale.