Houston Astros designated hitter Yordan Alvarez (hand) is "feeling better" but will remain sidelined on Sunday. Manager Joe Espada noted that Alvarez will likely not need imaging on his hand. This is a positive sign as it appears Alvarez is dealing with a minor injury. Fantasy managers should monitor his status leading up to their next game on Monday evening against the Milwaukee Brewers. This afternoon, Yainer Diaz will shift to the DH spot, which opens a spot for Victor Caratini to be behind the dish. Before his injury, Alvarez was having a slow start to the campaign, holding a modest .210/.306/.340 slash line with three home runs and one stolen base. However, under the hood, the slugger has generated an elite .495 xSLG and a .364 xwOBA, which are both well above the average marks. The Astros are worth targeting in DFS this afternoon, facing Chicago right-hander Bryse Wilson.

The Miami Marlins have placed infielder Otto Lopez (ankle) on the 10-day injured list prior to Sunday's game against the Athletics. In a corresponding move, the Marlins activated catcher Nick Fortes (oblique) from the 10-day injured list. Lopez was diagnosed with a Grade 2 ankle sprain after exiting Friday's contest early. As a result, fantasy managers should expect Lopez to spend longer than the minimum time on the injured list. This afternoon, the Marlins will give Javier Sanoja the nod at the keystone, and he will bat ninth. Before the injury, Lopez had posted a modest .229/.294/.330 slash line with two home runs and three stolen bases. Sanoja should see a majority of the opportunities at the keystone while Lopez is sidelined, with Ronny Simon mixing in.

New York Mets third baseman Mark Vientos is not in the starting lineup for Game 1 of a doubleheader on Sunday at Busch Stadium against the hosting St. Louis Cardinals. Luisangel Acuna will start in his place at third base and bat eighth versus Cardinals right-hander Erick Fedde. Despite the team's not playing on Saturday after the contest was postponed, Vientos will take a seat for the first game of the twin bill after starting each of the team's last 10 games. The 25-year-old is hitting just over .200 for the season with four home runs, 15 RBI and 15 runs scored, but he has picked things up of late, going 11-for-41 (.268) with two home runs, a double, triple, nine RBI and eight runs scored in his last 10 games since April 22. Acuna lacks much DFS upside near the bottom of the Mets' lineup on Sunday and he hasn't homered yet in 2025, but he's hitting a strong .289 (22-for-76) with four RBI, 13 runs and seven stolen bases.

Toronto Blue Jays outfielder Daulton Varsho (back) has been scratched from Sunday's starting lineup against the visiting Cleveland Guardians due to lower-back tightness, according to MLB.com's Keegan Matheson. Nathan Lukes will now patrol center field in the series finale at Rogers Centre against Guardians right-hander Tanner Bibee. Varsho has only played in five games in 2025 after getting a late start to the season due to offseason right-shoulder surgery. The 28-year-old has gone 3-for-14 with two home runs, three RBI, a steal and three runs scored. For now, fantasy managers should consider him day-to-day. Toronto has an off day on Monday before beginning a series in Anaheim against the Los Angeles Angels on Tuesday, so hopefully Varsho will be feeling better by then. He's a Gold Glover and the Jays' starting center fielder when he's healthy. Lukes will be a poor DFS choice in the eight-hole.

Athletics first baseman/outfielder Tyler Soderstrom is not in Sunday's lineup when the Athletics look to clinch a series victory over the Miami Marlins. Soderstrom has been in the starting nine in each game through the opening month. Soderstrom has enjoyed an impressive start to the campaign, posting a .277/.340/.523 slash line with five doubles and nine long balls. In addition, the Athletics have begun to give Soderstrom opportunities in left field as well as time at first base. Fantasy managers should expect the former 26th overall pick to return to the starting nine on Monday evening when they begin a series against the Seattle Mariners. As a result, this afternoon, prospect Nick Kurtz will cover first base and Miguel Andujar will cover left field.