Chicago White Sox starting pitching prospect Sean Burke took a tough loss in his second start of the campaign on Wednesday afternoon against the Minnesota Twins. Burke was able to log four 1/3 innings of work and allowed seven hits and six earned runs. He tallied just two strikeouts. He ran into trouble early, allowing a solo home run to Minnesota outfielder Byron Buxton in the first inning. Later in the fourth, he would allow a three-run shot to outfielder Harrison Bader. This was a tough outing for Burke, who performed quite well on Opening Day, as he tossed six shutout innings against the Angels. In that game, he allowed just three hits and struck out three. Last season, the former third-round pick received a brief taste of the majors as he logged 19 innings to the tune of a 1.42 ERA. He is worth holding in deeper 15-team formats as the White Sox will continue to provide him starting opportunities.

Toronto Blue Jays relief pitcher Jeff Hoffman gave up a run to the Nationals on Wednesday afternoon, but he still closed Toronto's 4-2 victory with his third save of the season. The 32-year-old righty entered the game in the ninth with a 4-1 lead and got the first two outs in quick succession before running into a little bit of trouble. He gave up a single, a double, and another single before his catcher Tyler Heineman threw out pinch-runner Jacob Young trying to steal second base to end the game. It was the first run allowed by Hoffman in his four games this season, and he is a perfect 3-for-3 in save opportunities. He will remain the team's primary closer as they head on a 10-game road trip to New York, Boston, and Baltimore starting on Friday.

Arizona Diamondbacks relief pitcher A.J. Puk had a wild ride in the ninth inning against the Yankees on Wednesday night, but he managed to close out the team's second straight win in the Bronx. Puk entered the ninth inning with nobody out after Ryan Thompson allowed singles to Cody Bellinger and Aaron Judge. Puk got Jazz Chisholm Jr. to fly out to RF but then allowed the inherited runners to score on a three-run blast off the bat of Anthony Volpe. The home run made the score 4-3 but Puk was able to retire Austin Wells and strike out Jasson Dominguez to secure the win and earn his second save. He is the only member of the Diamondbacks bullpen with a save this season and seems to be in the primary closer role ahead of Justin Martinez at least for now.

San Francisco Giants outfielder Luis Matos was a key contributor to the team's 6-3 win on Wednesday in Houston. He went 2-for-3 with a home run, a walk, and a strikeout. His homer was a solo shot to lead off the second inning against Framber Valdez, who struggled in his second start of the season and gave up five runs in five innings. Matos's big day improved his numbers on the season to 4-for-10 (.400) with a .528 wOBA in just three games. The 23-year-old is in the mix for playing time in the Giants' outfield but not currently locked in to an everyday role. More performances like this could earn him playing time, though, and he showed some power potential last season with 14 homers and a .340 wOBA in Triple-A.

San Francisco Giants relief pitcher Camilo Doval earned his second save of the season on Wednesday in Houston. He closed out the Giants' 6-3 win with a perfect ninth inning that required only 10 pitches. The 27-year-old righty has yet to allow a baserunner in his three appearances this season and has two saves, matching Ryan Walker for the team lead. Walker is typically the primary closer but has been unavailable the last two games due to back pain, and Doval has stepped in effectively. When Walker is available, he is expected to resume his role at the back end of the bullpen, but Doval has been very effective and is a strong backup option for the Giants. It looks like he would be the next man up if Walker ends up needing a trip to the injured list. The Giants are off on Thursday before opening a six-game homestand against the Mariners and Reds.