San Francisco 49ers

San Francisco 49ers tight end Eric Saubert was minimally involved but efficient in the team's passing game during a 27-24 loss to the Rams in Los Angeles. Saubert, filling in for George Kittle (hamstring), did good work in the run-block game and caught two-of-two targets for 41 yards. There are no updates on Kittle's injury at this time, but there are no indications that he's dealing with a multiple-week injury. Even if Kittle were to miss again, it seems likely that Sunday's performance is on the high side of what might be expected from Saubert in Week 4 versus the New England Patriots.

San Francisco 49ers wide receiver Jauan Jennings erupted in a 27-24 loss to the Rams in Los Angeles on Sunday. All he did filling in for Deebo Samuel Sr. (calf) was catch 11 of 12 targets for 175 yards and three touchdowns, not only nearly doubling Malik Nabers' overall WR2 performance, but leading all players at any position in fantasy thus far in Week 3. For gamers who took a lineup risk, Jennings caught the wide-open ones and the ridiculous ones alike, catching 10 straight after having the ball jarred loose on his first target. Jennings' output today obliterates his previous best outing when he had 94 yards and two touchdowns in the last game of his rookie year, 2021. Samuel Sr. is not expected to reclaim his starting role next week at home against the New England Patriots, so Jennings is in line for more opportunities to produce. He'll be a top waiver target in most leagues heading into Week 4.

San Francisco 49ers wide receiver Brandon Aiyuk once again disappointed in a 27-24 loss to the Los Angeles Rams at SoFi Stadium on Sunday. His final line amounted to five catches of 10 targets for 48 yards and no touchdowns. While technically an improvement from last week -- which was itself an improvement from Week 1 -- today's game had to sting for fantasy managers. Aiyuk's inefficiency juxtaposed with backup wideout Jauan Jennings' capture of all three receiving categories was frustrating, especially since we're almost a month removed from Aiyuk starting team workouts after a lengthy holdout. It's worth noting that Aiyuk's fantasy day -; and the 49ers' -; could have ended very differently had quarterback Brock Purdy seen him streaking down the middle wide-open behind the Rams' secondary in San Francisco's penultimate drive. Aiyuk's frustration was apparent when he was involved in a scuffle after San Francisco's last-gasp lateral play bounced off his hands near the Rams' sideline. There are no indications that any disciplinary action will follow. Perhaps Aiyuk will have renewed fire when the 49ers host the New England Patriots in Week 4.

San Francisco 49ers rookie running back Isaac Guerendo saw the first meaningful playing time of his career in a 27-24 loss to the Rams in Los Angeles on Sunday. The fourth-round pick out of Louisville entered with one carry for no gain through two games but took the ball five times for 19 yards in Week 3. It's conceivable that Guerendo's involvement could increase further in the next few weeks but it's very unlikely that he'll become startable in fantasy as long as Jordan Mason is healthy while filling in for Christian McCaffrey (Achilles). Head coach Kyle Shanahan has seemed to prefer a backfield bell cow situation throughout his tenure in San Francisco so Guerendo is a worthy stash in redraft formats as the next man up while McCaffrey is out in case of a Mason injury, but nothing more. Guerendo and the 49ers get the New England Patriots at home in Week 4.

San Francisco 49ers running back Jordan Mason returned to earth in a 27-24 loss to the Rams in Los Angeles on Sunday. He took 19 carries for 77 yards and caught both of his two targets for 11 yards receiving. As the stat line suggests, Mason wasn't bad in this one but failed to find the end zone for the first time this year, limiting his fantasy day. In the first two games of 2024, Mason completely dominated the running back touches but rookie Isaac Guerendo cut into his workload with five carries of his own for 19 yards against LA. It wasn't the RB1 performance that fantasy managers were looking for in Week 3 but Mason didn't look bad. There could come a time while Christian McCaffrey (Achilles) is out that Guerendo becomes even more involved, but it doesn't appear to be a worry just yet. Mason will resume his bell-cow role when the 49ers host the New England Patriots next Sunday.