San Francisco 49ers

San Francisco 49ers wide receiver Deebo Samuel Sr. (rib, oblique) is expected to suit up for Sunday's matchup against the Tampa Bay Buccaneers. The wideout was limited in practice throughout the week. However, it appears Samuel is in line to play, which is more great news for the 49ers, a team that is also expected to get Christian McCaffrey (Achilles) and Jauan Jennings (hip) back on the field. But as far as Samuel is concerned, he's caught only 24 passes for 406 yards and a touchdown this season, adding another score on the ground. Yet, with Brandon Aiyuk (knee) sidelined for the remainder of the 2024-25 campaign, Samuel should see an uptick in attention from Brock Purdy moving forward.

According to NFL Media's Ian Rapoport, San Francisco 49ers running back Christian McCaffrey (Achilles) will make his 2024-25 debut on Sunday against the Bucs. The 28-year-old hasn't played all season while dealing with bilateral Achilles injuries. But fantasy managers will finally get him back in Week 10. Although there's a chance he could see fewer snaps than usual, there's no way anyone should keep him out of their fantasy lineups. McCaffrey's expected return will cause Jordan Mason's fantasy ceiling to come crashing down. Still, Mason is worth holding on to for insurance purposes, considering McCaffrey has had issues staying off the injury report over the years.

San Francisco 49ers tight end George Kittle will take on the Buccaneers in Tampa for the team's Week 10 contest on Sunday. In Week 8 against Dallas, Kittle had a week-winning game, catching six of seven targets for 128 yards and a touchdown. The book on Kittle in fantasy has been boom/bust for years, but in 2024 it's been all boom. After a six-point game in Week 1, Kittle has outperformed projections in each subsequent game. He is now averaging 15.2 half-PPR points per game, while the second-ranked TE Brock Bowers sits at 11.2 PPG. It remains to be seen what the effect of an active Christian McCaffrey (Achilles) will be on Kittle's target share, but even if he takes a slight hit, he'll remain an elite option at an otherwise frustrating position. The Bucs present an excellent opportunity to keep the good times rolling, having allowed the third-most TE fantasy points this year. Unsurprisingly, Kittle is projected as the overall TE1 coming into Week 10.

San Francisco 49ers running back Christian McCaffrey (Achilles), who is listed as questionable to play in Week 10 against the Tampa Bay Buccaneers, said he feels great and is ready to make his 2024 debut on Sunday. McCaffrey missed the first eight games with bilateral Achilles tendonitis but completed his first full week of practice and will be activated from Injured Reserve on Saturday. CMC also dealt with a calf strain in early August and missed most of training camp in the summer. Now that the reigning Offensive Player of the Year is back, fantasy managers want to know how effective he'll be against Tampa and how much work he'll get. While McCaffrey should operate as San Fran's lead back on Sunday, he'll more than likely have his workload monitored, which will make him a more risky RB1. Jordan Mason will now lose most of his fantasy value as he reverts to a backup role.

San Francisco 49ers kicker Jake Moody (right ankle) logged a full practice on Friday and has been removed from the team's final injury report. As a result, he will play in Week 10 against the Tampa Bay Buccaneers. Moody has been sidelined since the end of Week 5, at which point he had gone 12-for-12 on extra points and 13-for-14 on field goals through five games. He earns significant volume as a result of the 49ers' strong offense, pairing his high usage with Moody's fantastic accuracy. The 24-year-old finds himself among the top 12 fantasy kickers for Week 10.