Pittsburgh Pirates third baseman Ke'Bryan Hayes (back) has returned from his back injury and is playing third base while hitting third on Friday in the series opener against the Boston Red Sox and right-hander Brayan Bello. Hayes is back in the lineup after missing the last two games with lower-back tightness. It obviously wasn't a serious issue for the 27-year-old, who will now look to get on track at the plate after an off day on Thursday. Hayes has hit .277 (18-for-65) in the early going but has yet to clear the fences and went 3-for-17 with five walks and six strikeouts in the previous five games before his back injury. Hayes has never faced Bello in his career.

Washington Nationals first baseman/outfielder Joey Gallo and third baseman Nick Senzel are both out of the starting lineup on Friday against the visiting Houston Astros. Joey Meneses is playing first base and batting sixth, while Ildemaro Vargas is at third base and hitting ninth against Astros right-hander Justin Verlander, who is making his 2024 debut after dealing with a right-shoulder injury this spring. Gallo started each of the team's previous 14 games and could use a break after hitting just .170 with three home runs to begin the year. Senzel began the year on the injured list and has gone 2-for-11 with a walk and three strikeouts in his first three games of the year. Meneses and Vargas have gone hitless against Verlander in their careers in just five combined at-bats.

Los Angeles Angels infielder Brandon Drury (hamstring) is back in the starting lineup on Friday against the Cincinnati Reds, serving as the designated hitter and batting fifth in the order. Luis Rengifo remains at second base and is batting seventh for the Halos. Drury missed the team's last three games with left-hamstring tightness but is back in action against his former team, the Reds. It's a good place for Drury to come alive with the bat in a hitter-friendly environment. So far in 2024 in his first 55 at-bats, Drury has been cold, picking up only 11 hits for a .200 batting average while hitting one home run, driving in three and scoring five runs. The Reds currently don't have a starter listed for Friday's contest yet.

New York Yankees infielder DJ LeMahieu (foot) said after undergoing an MRI exam on Thursday, doctors don't yet feel comfortable sending him on a minor-league rehab assignment. The hope is later this week he can start playing in games. When the 35-year-old is finally cleared, he's expected to begin a rehab assignment with Double-A Somerset. LeMahieu has yet to make his 2024 MLB debut with the Yankees after initially being expected to open the year as the team's regular third baseman. Manager Aaron Boone said that next Tuesday is now the target date for LeMahieu to begin his rehab assignment. Oswaldo Cabrera is starting at the hot corner for the Yankees on Friday against the visiting Tampa Bay Rays and left-hander Tyler Alexander.

The Colorado Rockies announced on Friday that they placed left-hander Kyle Freeland (elbow) on the 15-day injured list (retroactive to April 16) with a left-elbow strain and recalled right-hander Noah Davis from Triple-A Albuquerque in a corresponding move. Freeland injured his right, non-throwing shoulder on a slide into home plate as a pinch-runner earlier this week but is now dealing with a left-elbow injury. The 30-year-old southpaw could be out longer than just two weeks, depending on the exact nature of his elbow injury. It's unclear who will take Freeland's spot in the starting rotation, but it could be Davis. Freeland was scheduled to make his next start on Saturday against the Seattle Mariners. After a 13.21 ERA with eight walks and nine K's in his first four starts, fantasy managers in mixed leagues can drop him for now.