Houston Astros outfield prospect Joey Loperfido entered Friday's game with the most home runs in professional baseball. After Friday's game, he increased his lead with three more. Loperfido's three home runs brought in seven runs, raising his long-ball total to nine. The former Duke Blue Devil has a .320/.390/.880 stat line across his first 12 games of the season. Loperfido is making a case for an immediate call-up and is well worth stashing in redraft formats simply due to how well he is hitting the ball. He could also provide a much-needed spark to a struggling Astros team. When given the promotion, the 24-year-old could slot in the Astros outfield or at first base.

Pittsburgh Pirates closer David Bednar locked down the ninth inning for his second save of the season on Friday in a 5-2 win over the Phillies. After blowing three save opportunities already in the early going, manager Derek Shelton stayed true to his word that Bednar would still be the one he'd call on if a save opportunity arose in Philadelphia, and Bednar answered the call by pitching a clean inning. The 29-year-old didn't allow a hit or a walk and struck out one in the appearance. Hopefully the righty is back on track now. The Pirates (10-4) are a surprisingly competitive team thus far so they'll need Bednar to lock down more games for them. He did so last season for them 39 times to the tune of a 2.00 ERA, 1.10 WHIP, and a 21.3% K-BB%. So far in 2024, he holds a 10.13 ERA, 1.31 WHIP, and 23.1% K-BB%.

Texas Rangers starting pitching prospect Jack Leiter tallied ten punchouts across six innings in a loss on Friday evening. Leiter surrendered three earned runs and allowed six hits and no walks. Across 14 innings at Triple-A, Leiter is riding a 3.77 ERA and 0.98 WHIP with three walks and 25 strikeouts. This is a big step for his development, not only because he is holding his own at Triple-A and showcasing great strikeout potential but also because he has lowered his ratios significantly compared to his 5.19 ERA and 1.46 WHIP from last season. The former number two overall pick from Vanderbilt is putting all of the pieces together, and if he can continue his success at Triple-A, he could be in contention to make his major league debut this summer.

Baltimore Orioles third base prospect Coby Mayo launched his fourth and fifth home runs of the season on Friday evening. Mayo has been one of many Baltimore prospects crushing the ball at Triple-A. The 22-year-old is now sporting a .386/.444/.754 stat line through his first 13 games. He also has 10 RBI. Mayo is proving himself to be an elite power prospect as he is nearing double-digit home runs already and launched 29 last season. Mayo may have to wait a bit longer to make his major league debut, as the Orioles have a deep infield that just welcomed Jackson Holliday. Nonetheless, the third baseman will be a popular waiver-wire add when he receives the call to the majors later this summer, especially due to his power potential.

Pittsburgh Pirates pitching prospect Paul Skenes continued his dominance in Triple-A on Friday, throwing three shutout innings with three hits, one free pass, and eight strikeouts. The number three overall prospect is yet to surrender a run this season and has a minuscule 0.64 WHIP across nine and innings, with a total of 19 punchouts. Skenes, often touted as the best pitching prospect in baseball, is on the verge of making his major league debut, showcasing his elite fantasy ceiling with his dominant swing-and-miss potential. Already rostered in all dynasty and keeper formats, Skenes is a player worth checking your waiver wire for in shallower re-draft formats, as he will be a valuable player down the stretch.