Boston Red Sox first baseman Garrett Cooper (shoulder) has been scratched ahead of Wednesday's game against the Tampa Bay Rays. The right-handed slugger was in the original lineup, but has been pulled out due to right shoulder discomfort. Now, Dominic Smith will cover first base and bat sixth versus right-hander Ryan Pepiot. Fantasy managers should adjust their lineups accordingly.

Baltimore Orioles starting pitcher John Means (elbow) has been removed early during Wednesday's outing against the St. Louis Cardinals. The left-hander saw a decrease in velocity during his three innings before being taken out of the contest. The team is calling it left elbow discomfort, so the expectation is that Means will undergo further testing to determine the severity of the issue. Fantasy managers will need to check back for another update on his status.

Colorado Rockies starting pitcher Kyle Freeland (elbow) was able to throw a successful bullpen session on Wednesday. This was the first time that Freeland was able to throw since landing on the injured list due to a left elbow strain. The expectation is that Freeland will throw a few more bullpen sessions before going on a rehab assignment. There isn't a clear timetable for his return, but a return in middle or late June is possible.

Los Angeles Angels relief pitcher Luis Garcia was tasked with holding a one-run lead in the ninth inning of Wednesday's game against the Houston Astros. The right-hander blew the lead during the seventh inning of Tuesday's game. Despite that, Garcia was given another chance and worked a perfect ninth inning to earn his third save of the season. Garcia has been busy pitching in four of the last five games. The Angels bullpen situation is a little messy with Carlos Estevez as the primary closer, but Adam Cimber and Garcia are in the mix as well.

Los Angeles Angels starting pitcher Tyler Anderson was able to put together a solid outing during Wednesday's game against the Houston Astros. The left-hander allowed only one run over eight innings of work during Wednesday's victory. Anderson did allow six hits, but he was able to limit the damage. He now holds a 5-4 record with a 2.52 ERA to begin the season.