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CFB DFS Picks and Strategy for the Week 6 Slate (Saturday Early)

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We are already a quarter of the way through the college football season, which is insane to think about, and we have enough data at this point to make the best possible decisions when it comes to lineup construction. Week 6 offers a multitude of intriguing options and matchups with DraftKings posting a massive 14-game main slate.

In this slate breakdown, I will highlight the top plays at each position while also providing you with a core to build around in all formats. I will also include any advantageous PrizePicks or Underdog props as well as any betting opportunities. I haven’t forgotten about my FanDuel players and will list a player pool from their main set of games too.

Be sure to check out the latest episode of the CFB Supershow for game-by-game analysis from Jake Kucheck and myself. The live before lock show will take place Saturday morning at 11 a.m. ET, and there will be coverage of the other CFB slates throughout the day. Let’s get into it.

Vegas Odds

Team Odds Team Odds Total
Missouri 110 Texas A&M -130 (-2.5) 48
Boston College -108 Virginia -112 (-1) 53
SMU 205 Louisville -25- (-7) 56
Pittsburgh -148 (-3) North Carolina 124 64
Wake Forest 180 NC State -218 (-5.5) 54.5
Purdue 400 Wisconsin -535 (-14) 45
UCLA 1400 Penn State -3200 (-27.5) 46.5
Auburn 900 Georgia -1600 (-23) 52
Ole Miss -325 (-9) South Carolina 260 53.5
Virginia Tech -310 (-8) Stanford 250 49.5
Iowa 700 Ohio State -1100 (-19.5) 45
West Virginia 124 Oklahoma State -148 (-3) 64.5
Rutgers 205 Nebraska -250 (-6.5) 40.5
Alabama -1450 (-22) Vanderbilt 850 54.5

Quarterbacks

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