San Francisco 49ers

San Francisco 49ers rookie wide receiver Ricky Pearsall is in Tampa for a Week 10 matchup against the Buccaneers on Sunday. The 31st-overall pick in the 2024 draft will be playing in just his third game as a pro after an impressively short recovery from being shot in the chest as the victim of an armed robbery. Pearsall has a bright future but will be running as a third receiver this week with Deebo Samuel Sr. (rib/oblique) and Jauan Jennings (hip) expected to play. The 49ers are also welcoming back Christian McCaffrey (Achilles), and tight end George Kittle is healthy so targets will be hard to come by. Tampa Bay's pass defense hasn't been good, so the matchup is there for deeper-league managers looking to strike gold, but Pearsall should be considered a WR4 on Sunday, considering San Francisco's expected hierarchy.

San Francisco 49ers wide receiver Jauan Jennings (hip) will return from a two-game absence when the team takes on the Buccaneers in Tampa on Sunday. In his last time on the field -- in Seattle -- Jennings was targeted five times, finishing with three receptions for 27 yards. The targets tied Deebo Samuel Sr. for the wide receiver team lead, even with a pre-injury Brandon Aiyuk on the field. With Aiyuk out for the season, Jennings has a golden opportunity in front of him to become a fantasy contributor down the stretch. The matchup for 49ers receivers this week is good as the Bucs have allowed the seventh-most WR fantasy points this season. Consider Jennings a viable WR3/FLEX option in Week 10.

San Francisco 49ers running back Jordan Mason will return to a backup role in Week 10 when the team takes on the Buccaneers in Tampa. The undrafted third-year pro did an impressive job filling in for All-Pro Christian McCaffrey (Achilles) over the 49ers' first five games, averaging 15.9 half-PPR points before suffering a lingering shoulder sprain in Week 6 and ceding much of his subsequent work to rookie Isaac Guerendo. While Mason won't be completely locked out of action with the return of McCaffrey on Sunday since San Francisco is likely to ease the latter back into action to some degree, the Niners have established a preference for using their RB1 almost exclusively. As long as CMC remains healthy, Mason reverts to a top handcuff/stash, while Guerendo falls off the fantasy map entirely. Hang on to Mason if at all possible, but leave him on the bench in Week 10.

San Francisco 49ers quarterback Brock Purdy will be in Tampa for a Week 10 showdown against the Buccaneers on Sunday. The last time we saw Purdy, he earned a Week 8 30-24 victory over the Dallas Cowboys at home. The former Iowa State Cyclone looked sharp in that game, posting 26.3 fantasy points. Purdy has a juicy matchup coming out of the bye, as Tampa Bay's defense is ranked dead-last in QB fantasy points allowed in Yahoo default scoring. Though Purdy will be without Brandon Aiyuk (knee) for the remainder of the year, there are no other excuses for San Francisco's passing attack to stall in this one, as Christian McCaffrey (Achilles), Deebo Samuel (rib/oblique), and Jauan Jennings (hip) are all likely to play. The Bucs are leading the NFL in rushing touchdowns allowed to quarterbacks -- part of why they've been such a friendly matchup -- and Purdy has been on a bit of a ground-game heater. He's averaging 26.3 yards per game this season, nearly triple 2023's mark, and has rushed for three touchdowns in his last two games. However, McCaffrey's return is likely to stymie that trend. Regardless, Purdy is a solid fantasy starter in Week 10.

San Francisco 49ers wide receiver Deebo Samuel Sr. (oblique, ribs) is officially listed as questionable to play in the Week 10 matchup versus the Tampa Bay Buccaneers this Sunday, per head coach Kyle Shanahan. Samuel was limited in the first two practices of the week before shedding his non-contact jersey on Friday, so he's on the right side of questionable this weekend and should play after having last week's bye to heal up. In addition to Samuel likely being active against Tampa, Jauan Jennings (hip) and Chris Conley (ankle) have been cleared, which will make it more difficult for rookie Ricky Pearsall to stand out from a fantasy perspective. With Brandon Aiyuk (knee) out for the year, Samuel should be one of quarterback Brock Purdy's top targets going forward, making him a must-start in fantasy. Samuel caught four passes for 71 yards and carried the ball four times for 15 yards in Week 9.