San Francisco 49ers

San Francisco 49ers quarterback Brock Purdy (shoulder) was not spotted at Friday's practice, according to Nick Wagoner of ESPN. This is not a good sign for his ability this weekend, as he will likely carry an injury designation into the weekend. It was reported earlier on Friday that Purdy underwent a successful MRI but remained in questionable status. Fantasy managers should continue to monitor his status, but he could be in danger of missing Sunday's game. Purdy has enjoyed a great campaign from a fantasy perspective, averaging 26.0 PPR points per game since Week 6. If Purdy cannot play this weekend, Brandon Allen should be expected to take over starting duties and be viewed as a low-end QB2 in Superflex formats.

San Francisco 49ers quarterback Brock Purdy (shoulder) received positive results from an MRI, according to Cam Inman of the Bay Area News Group. Inman noted that general manager John Lynch expressed that the team feels "good" about where he currently is, but both Brandon Allen and Joshua Dobbs would be ready to suit up in case Purdy cannot play on Sunday. Fantasy managers should continue monitoring Purdy's status during Friday's practice as it would likely clarify his status heading into the weekend. If Purdy cannot suit up, Brandon Allen would be in line to see first-team reps and would be viewed as a low-end QB2 in Superflex formats facing the Green Bay Packers.

San Francisco 49ers running back Christian McCaffrey (Achilles) was rested on Wednesday in the first practice of the week before being limited in Thursday's session. McCaffrey isn't in any real danger of not playing in Week 12 against the Green Bay Packers on Sunday, but the 49ers will continue to take it easy on him during the practice week after he missed the first nine weeks of the season due to bilateral Achilles tendonitis. The 28-year-old hasn't scored for his fantasy managers in his first two games of the season, but he has gone over 100 scrimmage yards in both contests, which counts for something. In addition, backup Jordan Mason has been a distant No. 2 in terms of usage. The Packers defense has been middle of the pack this year in terms of fantasy points allowed per game to RBs, but they've given up the fourth-most fantasy points to the position in the last three weeks. CMC is a must-start RB1.

San Francisco 49ers quarterback Brock Purdy (shoulder) was listed as a limited practice participant for the second straight day this week on Thursday. Purdy also didn't speak to the media after practice on Thursday, instead opting to get extra treatment for his sore right shoulder. The 24-year-old's status is a bit up in the air for Sunday's game at Lambeau Field against the hosting Green Bay Packers, but the good news is he did more throwing in warmups than he did on Wednesday. In a worst-case scenario for the Niners, Purdy would be held out this weekend in favor of Brandon Allen under center. We'll have a better idea of Purdy's status after Friday's practice. If Purdy gets more done in Friday's practice and is cleared to play by Sunday, he should be considered a low-end QB1 option in fantasy against a Packers defense that has been more stingy against the position in recent weeks.UPDATE: Head coach Kyle Shanahan said he's hopeful Purdy will feel better and be able to play on Sunday.

San Francisco 49ers tight end George Kittle (hamstring) was limited in practice for the second straight day this week on Thursday. Kittle has been dealing with some hamstring irritation of late and was held out of the Week 11 loss to the division-rival Seattle Seahawks. The 31-year-old intends to return this Sunday to face the Green Bay Packers at Lambeau Field, though, and fantasy managers need to move him back into all starting lineups. He could be a little more risky as a TE1 in his first game back after missing last week, but Kittle has been the most productive TE for fantasy managers this year when active, so he's a no-brainer must-start if he's playing. Despite missing two games this season, Kittle is the TE2 in overall fantasy points, behind only rookie Brock Bowers. Kittle's seven touchdowns lead all tight ends.