San Francisco 49ers

San Francisco 49ers running back Christian McCaffrey did not register a touch during the 2024 NFL preseason. Many teams choose to rest their stars, and McCaffrey certainly fits that description. He's healthy and ready to go ahead of the upcoming season. Undoubtedly the best running back in the NFL, McCaffrey is coming off the second RB1 finish of his career in fantasy football. He eclipsed 2,000 scrimmage yards for the second time in his career last season and delivered a 21-touchdown campaign, which was a career-high. As long as McCaffrey stays healthy, he's the favorite to lead all running backs in fantasy points.

San Francisco 49ers wide receiver Brandon Aiyuk recently agreed to a four-year, $120 million contract extension, which included $76 million guaranteed. Although ESPN's Adam Schefter reported that was the same deal that "had been on the table," ESPN's Jeremy Fowler stated Aiyuk's decision to sign was based on wanting to get on the field. "Aiyuk wanted to play in games," said Fowler while appearing on NFL Live. "He didn't want to sit out and hold out of that portion of it. And then he was comfortable with the contract." The 26-year-old appeared in 16 games for the Niners last season, amassing a career-high 1,342 receiving yards with 75 catches and seven touchdowns. Without question, the end of the lengthy contract dispute has already resulted in Aiyuk seeing more attention during fantasy drafts heading into the 49ers' Week 1 meeting with the New York Jets.

San Francisco 49ers wide receiver Ricky Pearsall (chest) was released from the hospital on Sunday. The rookie wideout was the victim of a robbery attempt on Saturday, resulting in a gunshot wound to the chest. Fortunately, the bullet missed his vital organs. Pearsall, the No. 31 overall pick of the 2024 NFL Draft, likely has some hurdles to clear before he even considers returning to the field. But once he does, he'll have an uphill climb before he's relevant for fantasy managers outside of dynasty formats, considering the 49ers offense currently features Christian McCaffrey, George Kittle, Brandon Aiyuk, and Deebo Samuel Sr.

San Francisco 49ers wide receiver Ricky Pearsall (chest) was a victim of a robbery attempt on Saturday. According to reports, Pearsall was traveling to an autograph signing when he was approached by the suspect, who demanded the rookie's Rolex watch while brandishing a firearm. A struggle ensued for the gun, resulting in both Pearsall and the suspect sustaining gunshot wounds. The wideout was transported to a local medical facility and is now in stable condition. Police also caught the suspect. There should be an update on Pearsall's condition soon. While he'll likely miss time, his health beyond the field is undoubtedly more important.

San Francisco 49ers wide receiver Brandon Aiyuk has signed a four-year extension with the organization on Thursday. Finally, the drama is over as Aiyuk will be tied to the team for the next five seasons. The 49ers were forced to open their wallet as they will give Aiyuk $120 million over the next four seasons. Fantasy managers can now safely draft Aiyuk without any worries of him sitting out or a trade happening. Last season, Aiyuk finished with 75 receptions for 1,342 yards, and seven touchdowns in 16 games. The 26-year-old keeps getting better and should remain a focal point in this offense for years to come. He should have enough time to get ready in time for the regular season, so fantasy managers should have Aiyuk in their lineups for Week 1.UPDATE: The Athletic's Dianna Russini reports the 49ers were only willing to trade Aiyuk if they could get a top-tier receiver to replace him. They offered a third-round pick to the Broncos for Courtland Sutton and would have dealt Aiyuk to the Steelers, but the Broncos declined the offer.