San Francisco 49ers

San Francisco 49ers wide receiver Jauan Jennings (hip) has been ruled out for Week 7 against the Kansas City Chiefs due to a hip injury, according to head coach Kyle Shanahan. Jennings was unable to practice at all this week and could also be in danger of missing next week's contest against the Dallas Cowboys on Oct. 27. Brandon Aiyuk and Deebo Samuel (wrist) will operate as the team's top two receivers, as usual, but with Jennings sidelined, look for rookies Ricky Pearsall (chest) and Jacob Cowing, Chris Conley and Ronnie Bell to battle it out for the WR3 role as the Niners look for revenge against KC in a Super Bowl rematch. None of those names are worth risking in a flex spot in fantasy lineups this weekend. If anything, Jenning's absence will raise the ceiling and floor of Aiyuk, Samuel and tight end George Kittle. In deep leagues or DFS, Conley might be the best flex gamble.

San Francisco 49ers running back Jordan Mason (shoulder), who suffered a sprained AC joint in his left shoulder in the Week 6 win over the division-rival Seattle Seahawks last Thursday night, was taken off the final injury report on Friday and will play in Week 7 on Sunday against the Kansas City Chiefs in a Super Bowl rematch. The 25-year-old has been a must-start in fantasy lineups with Christian McCaffrey (Achilles) out all season, although he'll definitely carry more risk of an in-game setback this weekend. Rookie Isaac Guerendo filled in nicely and almost rushed for 100 yards after Mason left last Thursday, so the rookie could see a little more run to spell Mason against KC. But now that Mason has been officially cleared for Week 7, this is fantasy managers' cue to get him back into their starting lineups.

San Francisco 49ers running back Jordan Mason (shoulder) was seen wearing a non-contact jersey during Friday's practice, according to Nick Wagoner of ESPN. Mason has been a limited participant all week during practice and will likely carry an injury designation into the weekend as he has yet to shed the non-contact jersey. Fantasy managers should pay close attention to the injury report later on Friday as it may clarify the 25-year-old's availability for the weekend. Mason left last week's game early after suffering an AC joint sprain. If the standout running back happens to miss Sunday's game, rookie Isaac Guerendo will likely lead the San Francisco backfield and would become a viable RB2 play.

San Francisco 49ers running back Jordan Mason (shoulder) remains "up in the air" for Sunday's game, according to Ian Rapoport of the NFL Network. Mason suffered an AC joint sprain during last Thursday's game against the Seattle Seahawks. Mason logged two consecutive limited practice sessions on Wednesday and Thursday this week, which is a promising sign. Fantasy managers should pay close attention to Friday's injury report, as it will likely clarify the 25-year-old's status for the weekend. Mason has performed very well replacing the injured Christian McCaffrey (calf), running for 609 yards with three scores through six games, and should be locked into all lineups if he is able to play. If he cannot, rookie Isaac Guerendo should take the lead role.

San Francisco 49ers rookie wide receiver Ricky Pearsall (chest) has a good chance to make his professional debut this weekend, according to Matt Barrows of The Athletic. Barrows further noted that general manager John Lynch expressed that the rookie wideout has had a good practice weekend. Fantasy managers should pay close attention to Friday's injury report as it should clarify the 24-year-old's status heading into the weekend. Pearsall has been sidelined since suffering a gunshot wound before the opening week. If Pearsall can suit up, fantasy managers should consider stashing him on their bench but should be cautious inserting him into their lineup as he will likely operate as the No.4 pass-catching option in this offense behind Deebo Samuel Sr., Brandon Aiyuk, and George Kittle.