Isaac Guerendo's Stats, Metrics, Game Logs, Projections & Rankings

San Francisco 49ers rookie running back Isaac Guerendo will look to build on a modest increase in usage in Week 4 when the team hosts the New England Patriots. Last week against the Rams in Los Angeles, Guerendo took five carries for 19 yards and zero passing targets. The fourth-round pick saw his offensive snap count grow to 10 after combining for four total in his first two games. It's very unlikely that Guerendo will become usable for fantasy players in mainstream leagues without an injury to Mason, given head coach Kyle Shanahan's tendency to use his main back as a bell cow. In Week 4 Guerendo should remain on fantasy benches. However, he represents nearly as good an injury stash as any in the league, so managers who can afford to hold, should.

San Francisco 49ers rookie running back Isaac Guerendo saw the first meaningful playing time of his career in a 27-24 loss to the Rams in Los Angeles on Sunday. The fourth-round pick out of Louisville entered with one carry for no gain through two games but took the ball five times for 19 yards in Week 3. It's conceivable that Guerendo's involvement could increase further in the next few weeks but it's very unlikely that he'll become startable in fantasy as long as Jordan Mason is healthy while filling in for Christian McCaffrey (Achilles). Head coach Kyle Shanahan has seemed to prefer a backfield bell cow situation throughout his tenure in San Francisco so Guerendo is a worthy stash in redraft formats as the next man up while McCaffrey is out in case of a Mason injury, but nothing more. Guerendo and the 49ers get the New England Patriots at home in Week 4.

San Francisco 49ers running back Isaac Guerendo will handle kickoff returns in place of injured wide receiver Deebo Samuel Sr. (calf) in Week 3, according to Matt Barrows of The Athletic. Barrows notes that the majority of kickoffs in 2024 have resulted in touchbacks, but if the Rams attempt any kicks that are returnable, Guerendo will handle that duty. The 24-year-old rookie has seen minimal opportunities on offense this year, rushing just once while handling one percent of offensive snaps in Week 2. He's off the fantasy radar.

San Francisco 49ers running back Isaac Guerendo (groin) will suit up for Monday's game against the New York Jets. The rookie back missed over a week of practice due to a groin issue, but was able to get in a few limited practice sessions. Guerendo practiced in full on Saturday and has no injury designation ahead of Week 1. Lead back Christian McCaffrey (calf, Achilles) is listed as questionable ahead of Monday's game. Guerendo would likely see a significant workload if McCaffrey sits out which seems unlikely. That being said, Guerendo could see a few touches as the third string back. He looks more like a stash for fantasy managers in dynasty or deep leagues.

San Francisco 49ers running backs Elijah Mitchell (hamstring), Isaac Guerendo (hamstring) and Patrick Taylor Jr. (undisclosed) have all returned to training camp practices in the last two days. The only Niners running back out of practice still is starter Christian McCaffrey (calf), but he's been doing heavy work on the side. Mitchell will now try to hold off Jordan Mason for the RB2 role in San Fran. Although McCaffrey will end up missing the entire preseason, the 49ers aren't worried that he'll miss the start of the regular season. The 26-year-old former sixth-rounder in 2021 out of Louisiana would become a weekly fantasy option if CMC were to miss extended time, but Mitchell has battled injury issues of his own in his three years in the NFL and has played in a total of 27 games (12 starts) since entering the league. Guerendo is behind in his development heading into his rookie year, but he, too, could be a threat to Mitchell's spot on the depth chart eventually in 2024.