Isaac Guerendo's Stats, Metrics, Game Logs, Projections & Rankings

San Francisco 49ers rookie running back Isaac Guerendo (foot, hamstring) is expected to get back on the practice field on Thursday, according to head coach Kyle Shanahan. The rookie back is dealing with multiple injuries that kept him out of last week's game against the Miami Dolphins. His absence resulted in the 49ers using a committee approach in the backfield with two other backs sidelined as well. The hope is that Guerendo will be able to return for the Week 17 matchup against the Detroit Lions. He could be a low-end RB2 if he's healthy in time for that contest.

According to Matt Maiocco of NBC Bay Area, San Francisco 49ers running back Isaac Guerendo (hamstring) has been ruled out for Sunday's match against the Miami Dolphins. Guerendo was unable to participate in any team practices this week. He entered his Week 14 game with a foot injury and then left it with a hamstring concern. Fantasy managers should closely monitor his status next week as he may be in danger of missing more time. As a result, fantasy managers should expect Patrick Taylor Jr. to lead a depleted San Francisco backfield on Sunday. Throughout the season, he has tallied 50 yards on 14 attempts and brought in one of his two targets for 12 yards. Taylor should be viewed as a high-floor flex option this weekend facing a Miami rushing defense that has allowed the 12th-most PPR points to opposing RBs this season.

San Francisco 49ers rookie running back Isaac Guerendo (hamstring) is dealing with a hamstring injury and is unlikely to play in Week 16 versus the hosting Miami Dolphins at Hard Rock Stadium on Sunday, according to a source. The Niners' backfield has just been decimated by injuries this year, with Christian McCaffrey (knee), Jordan Mason (ankle) and Elijah Mitchell (hamstring) already out for the season. Guerendo handled himself nicely as the starting RB for San Fran the last two games, carrying the ball 31 times for 135 yards (4.35 yards per carry) and two touchdowns while catching all six of his targets for another 68 yards. Fantasy managers won't have him available for semifinal matchups this week, though, with Patrick Taylor Jr. likely sharing rushing attempts with receiver Deebo Samuel Sr. against Miami. Israel Abanikanda will also likely be available as a backup. Taylor will be an RB3/flex, at best, in fantasy.

San Francisco 49ers rookie running back Isaac Guerendo (hamstring) is not taking part in Wednesday's practice due to a hamstring injury. The rookie out of Louisville did not practice on Wednesday or Thursday last week due to a foot injury, so it appears he picked up a new ailment in last Thursday's loss to the Los Angeles Rams. Guerendo handled 100% of the team's running back touches (20) last week, but another injury could result in Patrick Taylor Jr. entering the fantasy football radar. Fantasy managers counting on Guerendo should pick up Taylor as an insurance policy for the fantasy football playoffs. The Dolphins present a neutral matchup for fantasy running backs, so whoever gets the start could have RB1 upside in Kyle Shanahan's offense.

San Francisco 49ers rookie running back Isaac Guerendo was inefficient during a 12-6 loss to the Los Angeles Rams in Santa Clara on Thursday night. There was some question coming into the game about whether Guerendo -- who spent the week questionable with a foot injury -- could fulfill head coach Kyle Shanahan's typical bell cow usage. Guerendo answered those questions emphatically by taking 16 of San Francisco's 18 carries, but he struggled to make them count, finishing with 57 yards and no touchdowns. He also caught all four of his targets for 18 yards, keeping his night in line with fantasy projections in PPR leagues. Assuming no aggravation of his injury, the fourth-rounder will be in play for lineups in Week 16 versus the Dolphins in Miami, who have been a mildly favorable matchup for running backs this season.