Arizona Cardinals

Arizona running back James Conner's Week 17 heroics, amassing 128 rushing yards and two touchdowns, highlight his dominant form heading into Week 18. With a four-game scoring streak, Conner needs just 110 yards to reach 1,000 for the season. Averaging 21.6 touches and 109.8 total yards since Week 13, he's a prime asset. Ranking 12th in explosive run rate, seventh in missed tackles forced per attempt, and eighth in yards after contact, Conner has been electric. Seattle's porous run defense, allowing the most yards and fifth-highest explosive run rate since Week 12, sets the stage for Conner's success in Week 18. Fantasy managers should confidently start him as he aims to continue his impressive run and end the season strong.

In Week 18, Arizona Cardinals' quarterback Kyler Murray carries the momentum from a stellar performance against the Eagles into a matchup against the Seattle Seahawks. Completing over 80% of his passes and scoring three touchdowns in a comeback victory in Week 17, Murray showcased his quarterback prowess. While his rushing output was modest, Murray remains a dual-threat force, ranking seventh in rushing yards and red zone carries per game. Despite his recent struggles as a passer, the Seahawks' defense, which has shown vulnerability in recent weeks, presents an opportunity for Murray to exploit. Since Week 12, Seattle has allowed significant passing yards, high yards per attempt, and a notable passer rating. With Murray's ability to capitalize on defensive weaknesses and a track record of at least 20 fantasy points in four of seven starts, deploying him in Week 18 could prove rewarding for fantasy managers. Murray is a QB1 for this matchup.

Arizona Cardinals wide receiver Zach Pascal (hamstring) logged another limited practice on Friday and is officially questionable to play against the Seattle Seahawks in Week 18. The 29-year-old has merely filled a depth role this season, catching four of 15 targets for 19 yards. He played 22 percent of offensive snaps last week with Marquise Brown (heel) on injured reserve but remains off the fantasy radar for Sunday's regular-season finale.

Jacksonville Jaguars wide receiver Zay Jones (knee, hamstring) is officially questionable to play in Week 18 after logging three limited practices in a row. Despite the vague injury designation, head coach Doug Pederson told the media that Jones will play on Sunday. His presence will be key for the Jaguars who haven't secured a playoff berth but do control their own destiny this week versus Tennessee. The Jaguars are somewhat shorthanded at wide receiver with Christian Kirk (core) on injured reserve and questionable to return this week. Assuming Jones operates as the Jaguars' No. 2 receiver, he'll rank as a mid-range WR4 option in most fantasy leagues.

Arizona Cardinals wide receiver Zach Pascal (hamstring) was downgraded to a limited practice participant on Thursday. Pascal has popped on Arizona's injury report with a hamstring issue after practicing fully on Wednesday, and it's unclear if it's a re-aggravation of the same problem that caused him to miss the Week 11 game against the Houston Texans, which was a strained hamstring. Either way, Pascal's presence on the field should not impact fantasy football in any capacity. The 29-year-old slot specialist has only corralled four of his 15 targets for 19 scoreless yards in 13 appearances during his first year in the desert. If Pascal cannot get the green light to play in Week 18's regular-season finale versus the Seattle Seahawks, Trey McBride, Michael Wilson, and Greg Dortch would be solidified as quarterback Kyler Murray's top targets.