San Francisco 49ers

San Francisco 49ers wide receivers Jauan Jennings (concussion) and Danny Gray (shoulder) are inactive for Sunday's game against the Los Angeles Rams. Both players had been listed as questionable. Jennings was limited in all three practices this past week but will ultimately miss his third consecutive game. Meanwhile, Gray has been on injured reserve since August, and while it seemed like there was a chance he could play this week, that won't be the case. Both Jennings and Gray could return for the playoffs, but they would merely occupy depth roles.

San Francisco 49ers quarterback Brock Purdy (coach's decision) is inactive for Week 18 versus the Los Angeles Rams. This was widely expected given that San Francisco has already secured the NFC's No. 1 seed and home-field advantage through the conference championship. Sam Darnold should start in place of Purdy, who will be joined on the sideline by star running back Christian McCaffrey (calf). As of now, Brandon Aiyuk, Deebo Samuel, and George Kittle are expected to play but could have limited roles in order to preserve their health.

San Francisco 49ers wide receiver Jauan Jennings (concussion) has been ruled out ahead of the Week 18 matchup against the Los Angeles Rams. As expected, Jennings will sit this game out which will make it his third in a row. To be fair, the 49ers don't have much incentive to play any of their starters with their postseason spot locked up. The hope is that Jennings will be ready in time for the postseason, but he hasn't contributed much on offense this season anyway.

San Francisco 49ers kicker Jake Moody will finish out his rookie season in a meaningless game at Levi's Stadium on Sunday versus the Los Angeles Rams. Moody has had a solid, if unspectacular start to his career, hitting 21 of 24 field goal attempts and making all 58 of his league-leading extra-point tries. He ranks as the overall K17 while ranking 27th in field goal attempts as a result. Los Angeles is the 11th-most generous defense to opposing fantasy kickers this year and the weather forecast looks mild for Sunday. Moody is downgraded a bit this week mostly because San Francisco's offense is expected to be diminished with backup quarterback Sam Darnold slated to start, although Moody remains a decent option for week 18 championships and DFS plays.

San Francisco 49ers tight end George Kittle has been great during the latter part of the season, ranking as the overall TE3 in half-PPR formats from Week 10 onward. Last week in Washington, however, he fell flat for fantasy managers playing for championships, having only mustered 4.4 half-PPR points. Kittle is risky this week versus the Los Angeles Rams, as the 49ers have locked up the No. 1 seed in the NFC and are resting quarterback Brock Purdy. Should the 49ers choose to diminish Kittle's snaps, there isn't much depth behind him with Ross Dwelley (ankle) out. The rest of the 49ers tight ends -- including those on the practice squad -- have combined for just 15 career targets. Consider Kittle a fantasy starter this week, but with some risk since San Francisco's personnel decisions outside of Purdy and Christian McCaffrey are unknown.