Arizona Cardinals

Arizona Cardinals wide receiver Michael Wilson remains a risky WR3/FLEX play in deeper leagues as he prepares to take on the Carolina Panthers. The 24-year-old has been a beacon of availability this season, playing at least 66 percent of offensive snaps in all 14 games. He has a modest stat line of 41 catches, 482 yards, and four touchdowns so far, ranking 52nd among wide receivers in terms of fantasy points (PPR). He had come on strong with 25.2 fantasy points between Weeks 13 and 14, but he dropped down to just 2.9 points with a pair of catches for nine yards last weekend. This week, Wilson faces the Panthers, who have been mediocre in terms of defending wide receivers. Carolina has allowed the 14th-fewest fantasy points to slot receivers this year, as well as the 12th-most fantasy points to receivers who play out wide. For context, Wilson has taken 212 snaps from the slot (30.6 percent), which is the 34th-most among NFL receivers. Managers can certainly justify starting him in deeper fantasy formats, but we'd advise looking elsewhere for production in leagues with 12 teams or fewer.

Arizona Cardinals tight end Trey McBride is arguably the No. 1 overall tight end play in fantasy football in Week 16 when the Cardinals travel to Carolina to take on the Panthers. McBride is having one of the best seasons we've seen from a tight end in recent memory, and statistically, the best in Arizona in a long time. One statistical category that is lacking is touchdown production, though. McBride just broke the record for most receptions in a season (89) without a touchdown. Cardinals quarterback Kyler Murray has been vocal about getting McBride into the end zone, and they will have a good opportunity to do so in Week 16, as the Panthers are allowing the most passing touchdowns in the NFL. It's hard to find a better option at the tight end position than McBride, and he should be started in all league formats.

Arizona Cardinals kicker Matt Prater (knee) has been ruled out for Week 16 against the Carolina Panthers. The veteran kicker had his 21-day practice window opened earlier this week, but the Cardinals have determined he's not quite ready to return from injured reserve yet. In the meantime, Chad Ryland will continue to handle kicking duties for Arizona. Through 10 games this year, he has gone 18-for-18 on extra points and 22-for-26 on field goals.

Arizona Cardinals rookie wide receiver Marvin Harrison Jr. is a flex play with great potential in Week 16. He and the Cardinals will travel to Carolina to face a defense that ranks 16th in fantasy points allowed to opposing receivers. Harrison Jr. has been boom or bust all season, and this week, he's presented with an opportunity to boom. He has been somewhat touchdown-dependent for fantasy production this season, and he will be facing a defense that has allowed the most passing touchdowns in the NFL. Despite not fully living up to the high expectations that come with being a top-five pick to this point, he has received over 90 targets this season and will be involved in Sunday's game plan. Harrison Jr. should be considered a flex play this week, with managers trusting him in their lineups.

Arizona Cardinals running back James Conner is a must-start RB1 in Week 16 when the Cardinals face the Carolina Panthers on the road. Conner will look to eclipse 1,000 rushing yards for a second straight season, entering this game with 973 yards. He has been a workhorse all year, posting ten games with 20 or more touches. The Cardinals have no margin for error if they want to keep their playoff hopes alive, and the offense has relied on Conner to carry the load. Since signing his contract extension, Conner has put together back-to-back games with 90 or more rushing yards. The vibes are high with Conner and the Cardinals' rushing attack, and fantasy managers should trust him in this matchup.